(redirected from Open angle glaucoma)
Also found in: Dictionary, Thesaurus, Medical.
Related to Open angle glaucoma: Closed angle glaucoma


(glôkō`mə), ocular disorder characterized by pressure within the eyeball caused by an excessive amount of aqueous humor (the fluid substance filling the eyeball). This causes pressure against the optic nerve and compression of the blood vessels of the eye—the resulting impairment of vision ranges from slight abnormalities to total blindness. Chronic open-angle glaucoma is the result of impeded drainage of aqueous humor. In acute angle-closure glaucoma, the anterior chamber of the eye is shallower and the iris may obstruct the meshwork at the entrance of the canal of Schlemm. Although glaucoma is a leading cause of blindness in the United States, with timely treatment blindness is almost always avoided.

Chronic glaucoma begins gradually over a period of months or years, usually in patients over the age of 40. There are no symptoms in the early stages, and the condition can be detected only by measurement of the intraocular pressure. Such an examination is recommended every three years for all persons over the age of 20. As the disease progresses, often the only symptom is a gradual loss of peripheral vision. Chronic glaucoma can usually be controlled with eye drops or pills that increase the outflow or decrease the production of aqueous humor; laser treatment is also effective in the early stages. If treatment is continued throughout life, useful vision will be preserved in most cases; untreated individuals will gradually become blind.

Acute closed-angle glaucoma, which accounts for only 10% of the incidence of the disease, begins abruptly with severe pain and blurred vision. It is a medical emergency that causes permanent blindness in two to five days if left untreated. Surgery is usually necessary.



(also called “yellow water” or “green water” in Russian—in glaucoma the region of the pupil sometimes begins to gleam with a yellowish gray or bluish gray light), a disease of the eyes, the principal symptom of which is an increase in intraocular pressure with a reduction of vision.

Intraocular pressure in glaucoma sometimes reaches 80 mm of mercury, or 10.67 kilonewtons (kN)/m2. (Normal pressure is 18-27 mm of mercury, or 2.4-3.6 kN/m2.) The pressure in the eye may rise spontaneously (primary glaucoma) or as the result of a previous or current disease of the eye (secondary glaucoma). The underlying cause of the disease is a disruption of the circulation of intraocular fluid—most commonly, difficulty in its drainage. Glaucoma usually develops in the elderly, often affecting both eyes, and as a rule proceeds chronically; in the absence of systematic treatment it is progressive. Glaucomas may be defined as either congestive (narrow angle), characterized by periodic clouding of vision, rainbowed halos around a light source, and a sensation of pressure in and around the eye, simple (open angle), in which these subjective phenomena are absent. In any form of glaucoma visual acuity gradually diminishes, the field of vision becomes limited, and the optic nerve atrophies. An acute attack of glaucoma, characterized by an abrupt rise in intraocular pressure, may develop at any stage of the disease; severe pains in and around the eye develop, there is reddening of the eyes, edema and clouding of the cornea, dilatation of the pupil, and reduction of vision, sometimes to the point of blindness. There is often accompanying nausea and vomiting. Glaucoma is the most common cause of blindness. The treatment may be medical or sometimes surgical. In the USSR prevention consists of examination of persons over 40 years of age and treatment of patients with established glaucoma at out-patient prevention and treatment clinics. Prevention of blindness from glaucoma involves early diagnosis of the disease and systematic treatment.


Averbakh, M. I. “Glaukoma.” In Oftalmologicheskie ocherki. Moscow, 1949.
Mnogotomnoe rukovodstvo po glaznym bolezniam, vol. 2. [Edited by V. N. Arkhangel’skii.] Moscow, 1960.



A disease of the eye characterized by increased fluid pressure within the eyeball.


a disease of the eye in which pressure within the eyeball damages the optic disc, impairing vision, sometimes progressing to blindness
References in periodicals archive ?
Timolol is a beta-blocker drug for the reduction of intraocular pressure in open angle glaucoma and ocular hypertension.
The publication of their results in EJO, which is available to a significant number of practicing ophthalmologists across Europe and around the world, adds additional credibility to PNT and should generate increased interest within the glaucoma community to take a closer look at our innovative procedure for treating primary open angle glaucoma and ocular hypertension," he said.
Refocus Group's PresVIEW Scleral Spacing Procedure for surgically treating presbyopia, primary open angle glaucoma and ocular hypertension utilizes four PresVIEW Scleral Implants, each about the size of a grain of rice, which are surgically placed in the four quadrants of the sclera (white of the eye).
Ocular Hypertension and Open Angle Glaucoma Markets: Physician Insights reveals that this market generated revenue of $1.
Called SLT/MED, the study is a multi-center, prospective, randomized and controlled study designed to investigate SLT as initial treatment for open angle glaucoma compared with topical medical therapy.
Avalos, Bores and LiVecchi's manuscript is just another step in our efforts to get the word out about PNT, and the versatility this approach offers in managing primary open angle glaucoma and ocular hypertensive patients.
Open angle glaucoma affects more than 50 million people worldwide, with more than 3 million cases in the United States alone.
Presby Corp and RAS Holding Corp own multiple domestic and international patents directed to methods, devices and systems for the treatment of Presbyopia, primary open angle glaucoma and ocular hypertension.
Elevated intraocular pressure is associated with primary open angle glaucoma, a leading cause of blindness, especially in African-Americans.
If successful, this program could lead to a breakthrough in the treatment of glaucoma, as it would become the first pharmacologic treatment to target the trabecular meshwork and address the true pathophysiology of primary open angle glaucoma.
This provides for detection and monitoring of Primary Open Angle Glaucoma, which represents approximately 80 percent of known glaucoma patients around the world.
Its systems are used in a variety of aesthetic, ophthalmic, surgical and dental applications, including skin treatments, hair removal, non-invasive treatment of vascular lesions and pigmented lesions, acne, psoriasis, ENT, gynecology, urinary lithotripsy, benign prostatic hyperplasia, open angle glaucoma, diabetic retinopathy, secondary cataracts, age-related macular degeneration, vision correction, neurosurgery, dentistry and veterinary.

Full browser ?