optical tweezers

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optical tweezers

[′äp·tə·kəl ′twēz·ərz]
(optics)
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It is possible to exploit this extraordinarily steep gradient for optical trapping, which is widely employed in both biology and physics due to its capability to precisely and noninvasively manipulate micron-sized and nanoscale particles (ranging from atoms and molecules to living cells and viruses [19-22]).
The process of optical trapping -- or optical tweezing, as it is often known -- involves sculpting a beam of light into a narrow point that produces a strong electromagnetic field.
This type of optical trapping is due to combined forces of direct gradient-force trapping and asymmetric photorefractive forces of electro-phoresis and dielectro-phoresis.
Although optical trapping of single cells may have negligible biological effects, it is highly dependent on the wavelength of laser light and the dosage of irradiation to which cells are exposed (40-42).
This strong gradient force that confines the objects in three dimensions has been exploited in dielectric nanostructures, leading to many exciting applications in colloid dynamics [2], particle sorting [3], lab-on-a-chip technology [4], optical trapping and transport of biomolecules [5,6].
In this work, we demonstrate for the first time the use of arrays of gold Bowtie Nanoantenna Arrays (BNAs) for multipurpose optical trapping and manipulation of submicrometer- to micrometer-sized objects.
Improving the PFS system made it compatible with things like multi-photon imaging and optical trapping, as well as ultraviolet calcium imaging.
The new techniques of atomic force microscopy (AFM; or scanning force microscopy) [1-4] and optical trapping (optical or laser tweezers) [5, 6] have allowed us to locate individual atoms and molecules on surfaces and to manipulate cells directly.
This research will open new opportunities for precise control of induced birefringence, which can be widely used in material processing, microscopy, and optical trapping and manipulation.
The sensitivity of optical detection is related to the laser linewidth, interaction length, and transverse mode overlap with the measurand; its potential of optically exciting ions or molecules and its optical trapping force are related to the laser intensity.
In the future," adds Nikon's Schwartz, "such important applications as optical coherent tomography and optical trapping, which are best used with longer wavelengths of light, will also become more widely explored.
This approach involves optical trapping technology capable of sensing single antigen-antibody bonds.

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