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Related to Oral hairy leukoplakia: lichen planus, Epstein Barr virus


Formation of thickened white patches on mucous membranes, particularly of the mouth and vulva.



milky-white spots (radius, to 0.5 cm) on the mucous membranes near the skin (for example, on the lower lip) and on the cheeks, tongue, bottom of the mouth, esophagus, cervix uteri, vagina, and urinary bladder.

Leukoplakia is one of the precancerous diseases. Smoking, advanced tooth decay, excessive consumption of alcohol or spices, certain inflammations of the oral cavity, avitaminosis A or B complex, and poorly fitting metal dental bridges, fillings, and crowns may give rise to leukoplakia. The disease occurs in two forms. In simple leukoplakia, the mucous membrane is smooth; its surface resembles mosaic or parquetry. This may be complicated by fissures or erosions. In verrucose leukoplakia, the mucosa is raised and the color varies from pearly to chalky. Patients complain of sensations of petrifaction, burning, and tenderness. Treatment is by surgical removal, electrocoagulation, or radiation therapy.

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4 Frequency of oral lesions has been reported to be decreased after antiretroviral therapy (ART) especially in case of oral candidiasis, oral hairy leukoplakia, necrotizing periodontal conditions and various AIDS related malignancies like Kaposi sarcoma.
Increased frequency of mucositis (2%), oral ulcers (6%), oral hairy leukoplakia (OHL) (3%), chronic periodontitis (26%) and oral wart (3%) were seen in ART group as compared to Non-ART group while oral mucosal pigmentation was significantly higher (63%) in ART group (p=0.
Oral candidosis and oral hairy leukoplakia as predictors of HAART failure in Brazilian HIV-infected patients.
Oral hairy leukoplakia and oral candidiasis as predictors of HIV viral load.
The examiner was trained to identify the following oral mucosal lesions: candidiasis (erythematous, pseudo-membranous and angular cheilitis), linear gingival erythema, oral hairy leukoplakia, aphthous ulcers, herpes simplex, Kaposi's sarcoma and lymphoma, which were photographed (Sony DSC-H2, San Diego, CA, USA).
Additionally, aphthous ulcers was present in six patients, herpes simplex in one, and oral hairy leukoplakia in five patients.
In the United Republic of Tanzania oral candidiasis and oral hairy leukoplakia were strong predictors for HIV infection.
The relationship between oral hairy Leukoplakia and Xerostomia.
They also had a 7%-10% lower rate of oral hairy leukoplakia than those not on such regimens; however, this rate did not achieve statistical significance.
While not all HIV-infected patients develop EBV-associated disease, persistent EBV replication and progressive immune dysfunction can eventually result in oral hairy leukoplakia and/or EBV-associated lymphoma.
Oral hairy leukoplakia is a painless, white lesion that usually arises on the lateral borders of the tongue (Figure 4).
Oral opportunistic viral infections include herpes simplex infections, oral hairy leukoplakia, varicella-zoster infections, cytomegalovirus infections and oral warts.