Among the subjects, 44 patients were on oral hypoglycemic agents
, 16 had been on insulin therapy for at least 5 years and 40 were on oral hypoglycemics as well as insulin therapy.
Those on TZDs and oral hypoglycemic agents
also had a significantly reduced risk (HR 0.
This product represents an interesting opportunity for Ranbaxy, in which we will offer a number of strengths of this oral hypoglycemic agent
to support dosing flexibility that will benefit both prescribers and patients.
Based on the approval of the partial change, the indication of TENELIAA has changed to type 2 diabetes mellitus based on the Guideline for Clinical Evaluation of Oral Hypoglycemic Agents
, and TENELIAA is now available for combination therapy with existing oral hypoglycemic agents
, such as biganides, ?
Drug Interactions with the following drugs or classes of drugs may occur: Antiarrhythmics, Anticonvulsants, Anti-HIV Agents, Antimycobacterials, Antineoplastics, Antipsychotics, Benzodiazepines, Calcium Channel Blockers, Gastric Acid Suppressors/Neutralizers, Gastrointestinal Motility Agents, HMG CoA-Reductase Inhibitors, Macrolide Antibiotics, Oral Hypoglycemic Agents
, Polyenes, Opiate Analgesics.
5 percent and no longer needing insulin or oral hypoglycemic agents
(blood sugar-lowering medications).
Whitehurst Professor of Medicine and professor of physiology "The data so far suggest that if both mom and the fetus have a GCK mutation, you may want to forego treatment [with oral hypoglycemic agents
or insulin], and even put mom on a high-carb diet, because the baby needs a high glucose level.
The primary end point--glycemic control at 12 months without the use of oral hypoglycemic agents
or insulin--was achieved by significantly more patients in the gastric bypass group (93%) than in the sleeve gastrectomy group (47%).
OBJECTIVE: To evaluate whether use of oral hypoglycemic agents
is associated with an altered breast cancer risk in women.
Currently, there are six major classes of oral hypoglycemic agents
available in the United States: agents that stimulate insulin secretion (sulfonylureas and rapid-acting secretagogues); reduce hepatic glucose production (biguanides); delay digestion and absorption of intestinal carbohydrates ([alpha]-glucosidase inhibitors); improve insulin action (thiazolidin-ediones [TZDs]); or inhibit glucagon release (dipeptidyl-peptidase 4 [DPP-4] inhibitors).
Gingko and garlic have increased the risk of bleeding with anticoagulants, while garlic has increased the hepatotoxicity of paracetamol and enhanced the effect of oral hypoglycemic agents
Denno KM, Sadler TW: Effects of the biguanide class of oral hypoglycemic agents
on mouse embryogenesis.