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Related to Organ development: Cell development


The formation of an organ.



the formation and development of organs in animals. Ontogenetic organogenesis is studied through embryology and biology of development, while phylogenetic organogenesis is studied through comparative anatomy. These disciplines describe and analyze the processes of organogenesis and explain the phylogenetic and ontogenetic origins of the processes. Comparative anatomy examines the rise of new organs and the transformation, division, progressive development and reduction, and rudimentation of organs. Study of the development of the forms of organs in connection with organ function led to the discovery of the basic principles of phylogenetic organogenesis—differentiation (seeDIFFERENTIATION), integration (seeINTEGRATION), and change of function.

To a large extent, ontogenetic organogenesis repeats phylogenetic organogenesis (seeBIOGENETIC LAW). Successive differentiation and integration of organs and uneven growth and active migration of cellular material occur in the course of ontogenetic organogenesis. The forces that underlie ontogenetic organogenesis can be precisely studied, especially by experiment. (For initial and subsequent stages of organogenesis seeDETERMINATION, CLEAVAGE, EMBRYONIC DEVELOPMENT, GERM LAYERS, INDUCTORS, INDUCTION, ORGANIZER.)

With respect to plants, “organogenesis” usually refers to the ontogenetic formation and development of basic organs—roots, stem, leaves, and flowers—from undifferentiated tissue, or meristem (seeMERISTEM).

References in periodicals archive ?
Their work, which hinged around studies of a tiny nematode worm, identified key genes regulating organ development and the programmed death of cells.
All three were recognised for their discoveries about how genes regulate organ development and cell death.
Childhood is a period of critical organ development and fast growth.
The University of Pittsburgh's McGowan Center for Artificial Organ Development, Pittsburgh, PA, announced that a novel resuscitative fluid it has created will be developed for commercial use as part of an agreement with Alteon, Inc.
Many malformations are the result of chromosomal abnormalities that cause defects during organ development in the womb.
Robert Horvitz, a co-recipient of the first Wiley Prize in 2002, shared the 2002 Nobel Prize for Physiology or Medicine for his respective work on how genes regulate organ development and cell death.
As actin remodelling and contraction has been associated with both generation of polarity and organ development, this project will address how actin-based contraction and specific actin-scaffolding/regulating proteins affect the formation of hepatocyte apical domains and BC.
Zebrafish research has already led to biological advances in cancer and heart disease research, and is advancing our understanding of muscle and organ development.
During critical periods of fetal organ development, IHC may result in a lack of oxygen and nutrient transport from the mother's blood to fetal circulation.
These address the key regulators of the cell cycle, genetic regulation of organ development and programmed cell death, magnetic resonance imaging, odorant receptors and the olfactory system, and bacteria related to gastritis and peptic ulcer disease.
Tumor necrosis factor-[alpha] (TNF-[alpha]) regulates a variety of biologic functions, including organ development, immune homeostasis, and malignance.
Its impacts on the immune and endocrine system, its impacts on organ development, particularly young babies, its impact on metabolism, its impact on gut flora, these are things that are not noticed by the person concerned until years later and it might be attributed to completely different causes.