Ornithine

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ornithine

[′ȯr·nə‚thēn]
(biochemistry)
C5H12O2N2 An amino acid occurring in the urine of some birds, but not found in native proteins.

Ornithine

 

H2N(CH2)3CH(NH2)COOH (also α, δ-di-aminovaleric acid), an amino acid that is readily soluble in water and alcohol.

Ornithine has one asymmetric carbon atom and exists in two optically active forms (D- and L-) and one racemic form, L-ornithine, found in the tissues of animals and humans, plays an important role in the biosynthesis of urea by the ornithine cycle. It is formed from arginine and α-amino-y-formylbutyric acid and may be converted to proline. Free L-ornithine is found in plants; bound L-ornithine is a component of several peptide antibiotics (bacitracin and gramicidin). L-ornithine has not been isolated from natural proteins.

References in periodicals archive ?
When exposed to sperm toxicants such as ORN or epichlorohydrin, male rats and mouse showed reversible infertility, with reduced sperm motility and decreased expression of DJ-1 in sperm and epididymides [17, 38].
The following epidemiological data were gathered retrospectively from medical charts: age, sex, pathological diagnosis, primary tumor sites, types of RT, radiation dose, chemotherapy, surgery for primary tumor, time interval between the end of RT and surgery for ORN, the existence of pathological fracture, location of ORN, and surgical findings (the extent of segmental mandibulectomy and bleeding at the resection margins).
Beyond empowering Vmembers of the LGBTI community, ORN has run programmes to increase the knowledge and understanding amongst the public on the issues the LGBTI community deals with and how these issues can be addressed.
The percentage of patients who required intervention for ORN (3.8%) is more consistent with the overall ORN rates from the literature, suggesting that most previous studies have captured only the more severe osteoradionecrosis, which is usually defined as that requiring a procedure, she explained.
The intention of this letter is to provide Nursing Council with suggestions to make the process of registration more user-friendly for overseas registered nurses (ORNs), without compromising the safety of the New Zealand public.
Only two survivors remain, Orn (Stone) and Volnard (Fiore Tedesco), left for dead among the still-breathing corpses--an early warning of the semi-amateur production values to come.
(25.) Porter to Welles, report, 16 January 1865, ORN, series 1, vol.
JQ: They're always shown in your films as complex, erotic beings, full of life and sex and sorrow: Orn in Blissfully Yours, some of the women in Haunted Houses, the two sisters and even the "older sister" singer in Tropical Malady, and the materialistic mother, "a proper Thai lady," in Iron Pussy.
Delrosal, NADEP San Diego, Calif.; Haukur Orn Johannesson, NAS Keflavik, Iceland; and James E.
NEW OSteoradionecrosis (ORN) is a potentially debilitating complication of radiation therapy in the treatment of carcinoma in and around the oral cavity.
Eriksson P, Viberg H, Jakobsson E, Orn U, Fredridsson A.