15,50) El uso de calcitriol y analogos sinteticos de vitamina D ha demostrado mejoria de la osteitis fibrosa
, la mineralizacion y el recambio oseo, a expensas de aumento en el riesgo de enfermedad adinamica osea.
A recent study; in which iPTH level was evaluated with radiologically evident erosions; the sensitivity, specifity and positive estimate value of iPTH levels over than 200 pg/ml for the diagnosis of osteitis fibrosa
cystica were found 83%, 88%, and 88%; respectively (29).
The patient was a man aged 38 who was crippled with advanced osteitis fibrosa
cystica, and who also complained of generalised bone pain, fatigue and weakness.
However, CKD patients are also at risk for other bone metabolic diseases, including osteitis fibrosa
cystica, osteomalacia, and adynamic bone disease, among others.
5) EPO resistance in patients can be due t o infections, chronic blood loss, osteitis fibrosa
, aluminum toxicity, primary hematological diseases, folic acid or vitamin [B.
123) Other pseudotumors with an endocrine underpinning include prostatic hyperplasias, (124,125) focal nodular hyperplasia of the liver (126) (Figure 14, A through D), ovarian stromal hyperthecosis, (127) the endometrial Arias-Stella reaction, (128) osteitis fibrosa
cystica (brown tumor of hyperparathyroidism) (129,130) (Figure 15, A through D), and uterine cervical microglandular hyperplasia.
cystica: the case of nine year old girl who also exhibits precocious puberty, multiple pigmentation of the skin and hyperthyroidizm.
Vertebral compression fractures, femoral and true fractures do not occur in osteomalacia unless complicated by tertiary hyperparathyroidism with osteitis fibrosa
Other potential etiologies that may affect the response to Epoetin alfa and should be considered when a patient is being assessed for hyporesponse include infection, inflammation, malignant processes, occult blood loss, underlying hematologic diseases, vitamin deficiencies, hemolysis, aluminum intoxication, osteitis fibrosa
cystica, and pure red cell aplasia.