In addition, the researchers showed that Cbf-beta maintains the osteoblast
lineage commitment in two ways: through the Wnt paracrine pathway to affect nearby cells and through endogenous signaling within the cell to suppress adipogenesis gene expression.
Alkaline phosphatase and production of collagen are extensively recognized indicators for osteoblast
function25 and their concentration increases with zinc supplementation.
Exposure of periodontal ligament progenitor cells to lipopolysaccharide from Escherichia coli changes osteoblast
For example, amlodipine, an L-type VSCC blocker, is used to treat MC3T3-E1 (immoral osteoblast
cell line) and MLO-Y4 (immoral osteocyte cell line) cells showing a prolonged declining of calcium in both types of cells, while treatment of NNC55-0396 (T-type VSCC blocker) can discontinue the repetitive influx calcium in MLO-Y4 cells after inducing an immediate spike, and it had no observable effects on MC3T3-E1 cells.
11) In a study, quercetin inhibited osteoblast
proliferation, differentiation, and mineralization.
The in vitro experiments with osteoblast
precursor cells indicated that both lead and fatty acids altered factors that influence Wnt signaling.
OCS inhibit osteoblast
maturation, secretion and transformation into osteocytes.
2010) are likely to exhibited osteogenic activity in calvarial derived osteoblast
Rucinski et al  investigated the effects of estradiol and some resveratrol like silymarin on osteocalcin gene expression in Osteoblasts
primary cells and found that despite estradiol, Silymarin could not alter osteocalcin gene expression in osteoblast
29 This signal molecule en- hances vascular invasion stimulates proliferation of osteoblast
precursors and promotes mineralization of new bone by osteoblasts
13] that reported increase in normal osteoblast
and reduction in osteosarcoma cells after treating with LLLT with 830 nm wavelengths and total energy impact of 10 J/cm2.
Wnt/[beta]-catenin signaling plays significant roles in both embryonic development and tumorigenesis, and when activated induces differentiation of mesenchymal cells with pluripotential into osteoblast
progenitors to become osteoblasts