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Any defective bone formation, as in rickets or dwarfism.



any one of a group of bone diseases that are characterized by deformity of different parts of the skeleton owing to metabolic disorders. Osteodystrophy can be parathyroid, deforming, local fibrous, toxic, or related to diseases of the internal organs; the first two types are the commonest. Spontaneous bone resorption is the extreme type of osteodystrophy.

Parathyroid osteodystrophy is an endocrine disease that develops with parathyroid tumors and with the release of excess quantities of parathyroid hormone. Considerable resorption occurs throughout the skeleton. The treatment is surgical, involving resection of the parathyroid gland. Unlike parathyroid osteodystrophy, deforming osteodystrophy affects one or only a few bones. The pathogenesis of deforming osteodystrophy is unknown, and treatment is symptomatic. Deforming osteodystrophy is conducive to the development of osteosarcomas.

References in periodicals archive ?
Renal osteodystrophy is described as the osseous sequelae of hyperparathyroidism secondary to renal failure where calcium from the bone is mobilized to replenish the body's calcium requirements.
The role of serum cytokines in the pathogenesis of hepatic osteodystrophy in male cirrhotic patients.
Renal osteodystrophy occurs in patients with advanced CKD and includess hyperparathyroidism-mediated high turnover bone disease, adynamic bone disease, osteomalcia, and mixed uremic osteodystrophy (Miller, 2014).
Because of renal osteodystrophy, these patients have lower bone mineral density than non-renal patients.
Based on clinical signs, radiographic findings, and interpretation of plasma vitamin D levels, treatment for hypovitaminosis D and orthopedic abnormalities associated with osteodystrophy were initiated immediately.
The renal osteodystrophy pattern in Brazil and Uruguay: an overview.
Hand X-rays are valuable to evaluate the severity of osteodystrophy and the growth potential.
Furthermore, there are numerous painful syndromes unique to CKD such as calciphylaxis [17], renal osteodystrophy [18] and amyloidosis [19].
Subjects were excluded if they had (a) clinical or imaging evidence of renal osteodystrophy or other metabolic bone diseases other than osteoporosis or a known malignancy, (b) a history of lumbar spinal surgery or irradiation, or (c) MR imaging evidence of large intravertebral disk herniation, hemangioma, or moderate-to-severe vertebral fracture of L3.
The differential diagnosis of OCI is sacroiliitis, seronegative spondyloarthropathies-especially ankylosing spondylitis (AS), lumbar or piriformis strain, ischio-gluteal bursitis, renal osteodystrophy, lymphoma, Paget's disease, primary hyperparathyroidism, and metastatic diseases (2).
Grynpas (2004) Association Between Fluoride, Magnesium, Aluminum and Bone Quality in Renal Osteodystrophy.