oxazole

(redirected from Oxadiazoles)
Also found in: Medical.

oxazole

[′äk·sə‚zōl]
(organic chemistry)
C3H3ON A structure that consists of a five-membered ring containing oxygen and nitrogen in the 1 and 3 position; a colorless liquid (boiling point 69-70°C) that is miscible with organic solvents and water; used to prepare other organic compounds.
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References in periodicals archive ?
Sharma, Synthesis and biocidal activity of some substituted oxadiazoles, thiadiazoles and triazoles, Indian J.
Pitsas, Synthesis of Novel Sulfonamide-1,2,4- Triazoles, 1,3,4-Thiadiazoles and 1,3,4- Oxadiazoles, as Potential Antibacterial and Antifungal Agents: Biological Evaluation and Conformational Analysis Studies.
The significant biological activities of 1,3,4- Oxadiazoles, amides and Schiff bases prompted us to synthesize some new molecules bearing all these functionalities.
Khan and Atta-Ur-Rahman, Kinetics of Novel Competitive Inhibitors of Urease Enzymes by a Focused Library of Oxadiazoles / Thiadiazoles and Triazoles, Biochem.
e 124 oxadiazoles which have engrossed the interest of researcher due to their worth importance in the field of material sciences polymer insecticidal and medicinal [17].
Due to medicinal importance and in continuation of our previous research work on 1,3,4- Oxadiazoles [9-12], the 2,5-disubstituted-1,3,4- Oxadiazole derivatives were synthesized with an objective to detect the biological potential.
Polymers containing 1,3,4-oxadiazole rings present a great interest for high performance materials because of their high thermal stability and certain specific properties that are determined by the nature of oxadiazole unit that has a strong electron-withdrawing character [1, 2], Poly(arylene-oxadiazole)s give easily redox reactions, chemically or electrochemically, and the resulting materials are good candidates for electrochemical sensors or electroluminescent devices, to be used in optoelectronics, microelectronics, or other advanced fields [3, 4].
Poly(aryleneoxadiazole)s, which are of special interest for the production of advanced materials due to their high thermal oxidative stability and specific properties, are determined by the electron withdrawing nature of oxadiazole units.
In the FTIR spectrum of compound C (-l), absorption peaks at 1520 and 1340 cm (-1) are due to the asymmetric and symmetric stretching vibrations of nitro groups, and weak bands located at 1553 and 956 cm (-1) correspond to the stretching vibration of C=N and C--O--C in oxadiazole ring, respectively (35).
In this study, it was planned to incorporate the oxadiazole ring system into tetrazole ring, as it has not been reported earlier.
Our aim was to synthesize the new chemical entities derived from santonin with oxadiazole moiety and to evaluate them for the antimicrobial activities.