Hugo Schiff

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Schiff, Hugo


Born Apr. 26, 1834, in Frankfurt am Main; died Sept. 8, 1915, in Florence. Italian chemist. German by nationality.

A student of F. Wöhler, Schiff was a privatdocent at the University of Bern (1857). He later emigrated to Italy, where he worked in Florence from 1863 to 1876 and from 1879 to 1915. From 1876 to 1879 he was a professor at the University of Turin.

Schiff’s main works were devoted to organic chemistry. Schiff discovered the condensation reaction of aromatic amines with aldehydes (1864) and investigated the products of the reaction, which have come to be called Schiff bases. He synthesized populin (1868) and digallic, or tannic, acid (1873). He proposed qualitative reactions for aldehydes (with fuchsin sulfurous acid; called the Schiff reaction), urea, and pentosanes. Schiff invented the azotometer (or nitrometer), a device for determining nitrogen according to the method proposed by J. B. Dumas.


“Hugo Schiff.” In the collection Berichte der Deutschen chemischen Gesellschaft, fasc. 48, vol. 2. Berlin, 1916. Pages 1566–67.
References in periodicals archive ?
In another study by Machler et al routine histologic examination with PAS stain was found to be equal to culture and superior to KOH in leading to a diagnosis of dermatophyte infection of nail5.
For malakoplakia containing foamy macrophages with basophilic inclusions called Michaelis Gutmann bodies were identified by PAS stain.
6,7] This typical histologic appearance is referred to as the Splendore-Hoeppli phenomenon and can be seen using gram stain, Giemsa stain, PAS stain or silver stain.
The PAS stain is useful for identifying glycogen, but removing glycogen with diastase digestion enhances the detection of non-digested material, including debris within macrophages.
The histopathology of the nail clippings sample treated with a PAS stain demonstrates fungal elements and is the most sensitive test, but it does not identify the species.
The PAS stain performs almost as well as GMS, in screening for fungi.
Histologic evaluation of a sample of nail clippings using PAS stain also can be ordered to identify the infecting organism.
c) Diastaseresistant eosinophilic globular inclusions, PAS stain with diastase.
Caption: Figure 4: Nodular-to-diffuse, pyogranulomatous panniculitis with numerous Prototheca-Hke elements stained vividly purple with PAS stain.
Visualization of the yeasts on 10% KOH preparation, Gomori's stain, PAS stain, or Papanicolaou's smear of tissue biopsy, tracheal aspirates, BAL fluid, and sputum specimens or tissue cytological analysis or fungal culture on Sabouraud dextrose agar at room temperature are some basic methods for diagnosis of the Blastomyces dermatitidis infections.
Providing a history and the physical characteristics of the rash or a differential diagnosis will prompt the performance of a PAS stain.
In our case, there was definite invasion of the fungal bodies into the deeper layers of granulation tissue (figure 2), which was well seen on the PAS stain (figure 4).