cyclic nucleotide phosphodiesterase

(redirected from PDE3B)
Also found in: Medical.

cyclic nucleotide phosphodiesterase

[¦sīk·lik ‚nü·klē·ə‚tīd ‚fäs·fə·dī′es·tə‚rās]
(biochemistry)
Any of a group of enzymes that degrade cyclic nucleotides.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
Mentioned in ?
References in periodicals archive ?
The PDE3B mutation appears to protect against heart disease.
Insulin inhibits this process through the phosphoinositide 3-kinase-dependent (PI3K) pathway, protein kinase B (PKB/Akt), and activation of phosphodiesterase 3B (PDE3B), which degradates cAMP.
In addition, CUGBP1 negatively regulates insulin secretion by stabilizing phosphodiesterase subtype 3B (PDE3B) [186].
Of the PLC samples, we found that the transcriptional expressions of MLH3, ACSL6, CD55, CR1, PDE3B, CCNB1, PAICS, SEC62, BIRC3, TCF7, NT5E, and PSPH in the PBMCs of gan-shen Yin deficiency group were significantly lower than those in non-gan-shen Yin deficiency group (Figure 1(a), p < 0.05).