cyclic nucleotide phosphodiesterase

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cyclic nucleotide phosphodiesterase

[¦sīk·lik ‚nü·klē·ə‚tīd ‚fäs·fə·dī′es·tə‚rās]
(biochemistry)
Any of a group of enzymes that degrade cyclic nucleotides.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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The PDE3B mutation appears to protect against heart disease.
Cholesterol Genetics
Insulin inhibits this process through the phosphoinositide 3-kinase-dependent (PI3K) pathway, protein kinase B (PKB/Akt), and activation of phosphodiesterase 3B (PDE3B), which degradates cAMP.
Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue
In addition, CUGBP1 negatively regulates insulin secretion by stabilizing phosphodiesterase subtype 3B (PDE3B) [186].
Long Noncoding RNAs and RNA-Binding Proteins in Oxidative Stress, Cellular Senescence, and Age-Related Diseases
Of the PLC samples, we found that the transcriptional expressions of MLH3, ACSL6, CD55, CR1, PDE3B, CCNB1, PAICS, SEC62, BIRC3, TCF7, NT5E, and PSPH in the PBMCs of gan-shen Yin deficiency group were significantly lower than those in non-gan-shen Yin deficiency group (Figure 1(a), p < 0.05).
Reduced MLH3 Expression in the Syndrome of Gan-Shen Yin Deficiency in Patients with Different Diseases

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