References in periodicals archive ?
Competition between glucose and fatty acids for oxidation occurs at the level of the PDH complex, whose activity is decreased by PDKs.
2011) indicates that both the biotransformation of DCA and the site of its major pharmacodynamic action, the PDH complex, occur within the matrix of this organelle.
In two patients, PDHc deficiency was confirmed to result from disease-causing mutations in the E1[alpha] gene of the PDH complex. In five patients, mutation analysis of this gene did not reveal any disease-causing mutation, suggesting an involvement of other components of the PDHc.