All patients had PNH
diagnosed by flow cytometry, and 61% had begun eculizumab therapy before conception.
Currently, severe cases of PNH
are treated with eculizumab (Soliris), however due to the cost of the drug, widely considered to be one of the most expensive drug in the world, the majority of patients are monitored and treated with symptomatic and supportive approaches such as: folic acid (folate) supplements, anticoagulation therapy, steroids, growth factors, blood transfusions and bone marrow transplants.
functions not only with the funds that are donated by individuals and businesses but also by working with other nonprofits to satisfy the requirements of certain grants.
Alexion is the global leader in complement inhibition and has developed and markets Soliris([R]) (eculizumab) as a treatment for patients with PNH
and aHUS, two debilitating, ultra-rare and life-threatening disorders caused by chronic uncontrolled complement activation.
Treatment of PNH
is generally supportive and consists of transfusion, folate supplements, and corticosteroid and androgen therapy (16).
We are now looking to conclude the sale of our remaining Admiral territories and we are delighted to be working with PNH
and hope to finalise our divestment from the sports licensing sector shortly, allowing us to utilise these funds to further build our diagnostics business.
SHEPHERD and TRIUMPH Phase III clinical trials, which also showed significant reductions in hemolysis, anemia, transfusion dependence, and fatigue among patients with PNH
in the U.
Alexion acquired exclusive world-wide rights to FLAER, a highly sensitive diagnostic test for PNH
There are no therapies specifically available for the treatment of PNH
The TRIUMPH trial included 87 PNH
patients and the SHEPHERD trial has enrolled 97 PNH
Other severe complications of PNH
include deficiencies of other blood cell types and thrombosis, both of which can cause death.
accounts for a large share of the eardrop market in Nashville, Tenn.