PS1

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PS1

PS1

(1) Sony's PlayStation 1. See PS one.

(2) (PS/1) An early IBM PC. See IBM PS/1.
References in periodicals archive ?
EOAD: Mutaciones en Biomarcadores en la los genes APP, PSEN1 enfermedad de y PSEN2.
Wallon et al., "APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer's disease: a genetic screening study of familial and sporadic cases," PLoS Medicine, vol.
PSEN1 and PSEN2 are part of the [gamma]-secretase complex, which also includes nicastrin, anterior pharynx-defective 1, and presenilin enhancer 2 [29].
levels are consistently higher in individuals destined to develop Alzheimer's as compared to healthy controls both in autosomal dominant carriers (mutations found in APP, PSEN1 and PSEN2 genes) and in Down syndrome patients.
Presenilins are transmembrane proteases that in humans are represented by two homologs, presenilin-1 (PS-1) and presenilin-2 (PS-2), encoded by two gens, PSEN1 and PSEN2, respectively [85].
Li et al., "The miR-193a-3p regulated PSEN1 gene suppresses the multi-chemoresistance of bladder cancer," Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, vol.
A comprehensive dystonia next generation sequencing panel was sent to Medical Neurogenetics in 2014 and showed one variant of uncertain significance (VUS) in PSEN1 and one VUS in DDC.
Wallon et al., "PSEN1, and PSEN2 mutations in early- onset Alzheimer disease?: A genetic screening study of familial and sporadic cases," PLoSMed, vol.
Genetic linkage analyses of familial cases have led to the identification of causative mutations in three genes, APP, PSEN1, and PSEN2, as well the identification of a high-risk factor: the E4 allele of APOE [3].
Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset alzheimer's disease families.
Los dos genes Presenilina 1 (PSEN1) y Presenilina 2 (PSEN2), que codifican respectivamente las proteinas presenilina 1 (PS1) y presenilina 2 (PS2), contribuyen al complejo secretasa.