propylthiouracil

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propylthiouracil

[‚prō·pəl¦thī·ō′yu̇r·ə‚sil]
(pharmacology)
C7H10N2OS White, crystalline powder with a melting point of 218-221°C; soluble in ammonia and alkali hydroxides; used in medicine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The BIR requires businesses to submit their sales reports through the eSales system every eight or tenth of the month, to be complied with using the new MIN as provided on the new PTU generated.
CRP: C-reactive protein; free T3: free triiodothyronine; free T4: free thyroxine; KI: potassium iodide; MPOANCA: myeloperoxidase-anti-neutrophil cytoplasmic antibody; MTX: methotrexate; PR3-ANCA: proteinase 3-anti-neutrophil cytoplasmic antibody; PSL: prednisolone; PTU: propylthiouracil; RI (13mCi): radioisotope (13mCi); TSH: thyroid-stimulating hormone.
Interestingly, PTU as well as the 2-week T4 recovery repressed the T4-induced LV systolic dysfunctions as indicated by significantly improved EF (PTU + T4: 64.79 [+ or -] 1.52% and recovery: 70.93 [+ or -] 1.09%; P < 0.001) (Figure 1(a)) and FS (PTU + T4: 35.12 [+ or -] 1.12 and recovery: 39.850 [+ or -] .8383%; P < 0.001) (Figure 1(b)).
PTU should not be given to pregnant women due to potential teratogenic effects (Vallerand et al., 2015).
The 5and 15-day PTU treatment induced decreases in the ventricle muscle Mb mRNA content of 60% and 20%, respectively (Figure 2B and C).
(2) O PTU tambem pode ser usado, pois nao causa alteracoes na funcao tireoidiana nem no desenvolvimento fisico e psiquico do recem-nascido, porem deve ser lembrado o risco de hepatotoxicidade.
The majority of cases of vasculitis (88%) have been reported in association with PTU, vasculitis associated with carbimazole is very rare (5, 6, and 7).
Treatment in the other 3 patients was switched from MMI to PTU or potassium iodide and their symptom resolved.
Haemoglobin showed a reduction (p < 0.001) in the 2nd and 3rd collections both for the CTU and control groups, while for PTU the reduction occurred only in the last collection, although with no differences among groups (p < 0.966) and interaction (p < 0.513).
Buildup of GDD and PTU are good estimators to study wheat phenology and can be used as reliable tool to optimize the sowing period for different wheat cultivars (Pal et al., 1996; Prabhakar et al., 2007).
* Use propylthiouracil (PTU), if available, as the first-line drug for treatment of hyperthyroidism during the first trimester.