Paget's disease

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Paget's disease

[′paj·əts di‚zēz]
(medicine)
A type of carcinoma of the breast that involves the nipple or areola and the larger ducts, characterized by the presence of Paget's cells.
Osseous hyperplasia simultaneous with accelerated deossification.
An apocrine gland skin cancer, composed principally of Paget's cells.
References in periodicals archive ?
Flow chart showing (from top to bottom) the number of mammary Paget disease cases (MPD); the frequency of estrogen (ER) and progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and high Ki-67 expression in cases of mammary Paget disease; the results of HER2 chromogenic in situ hybridization (CISH) in cases of mammary Paget disease; the frequency of molecular subtypes of mammary Paget disease; and the molecular subtypes of associated invasive carcinoma of the breast (ICB), in cases in which the molecular subtype of the mammary Paget disease was also known.
Endothelial expression of PSMA in neovasculature known to occur in Paget disease has been postulated as the mechanism causing the PSMA-PET/CT positivity of this condition [5-8].
Ozawa et al., "Androgen receptor, androgen-producing enzymes and their transcription factors in extramammary Paget disease," Human Pathology, vol.
Tan, "Extramammary Paget disease: immunohistochemistry is critical to distinguish potential mimickers," Dermatology Online Journal, vol.
[Usefulness of magnetic resonance imaging in Paget disease of the breast] J Radiol.
The third edition of this reference volume on breast cancer contains updated information on risk factors, cancers associated with different genes, inflammatory breast cancer, Paget disease of the nipple and breast cancer in men.
The FDA continues to monitor postmarketing reports of atrial fibrillation in people treated with bisphosphonates, which are approved for treating osteoporosis, Paget disease, and for some cancer-related indications.
This issue's cover was inspired by the article on Paget disease.
These disorders include hereditary myopathies and acquired myopathies, such as GNE myopathy, inclusion body myopathy with Paget disease of bone, frontotemporal dementia (IBMPFD),[sup][1] oculopharyngeal muscular dystrophy (OPMD),[sup][2] oculopharyngodistal myopathy (OPDM)[sup][3] sporadic inclusion body myositis (s-IBM),[sup][4] and so forth.