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Related to Pancreatitis: Gallstones, pancreas, Chronic pancreatitis


Inflammation of the pancreas.



acute or chronic inflammation of the pancreas.

Acute pancreatitis may be edematous, hemorrhagic, necrotic, or purulent. It is caused by overeating; by diseases of the stomach, duodenum, biliary tract, or liver; or by stenosis of the gland’s ducts. In acute pancreatitis the pancreas is digested by its own enzymes—trypsin, chymotrypsin, and lipase. When the gland’s tissue decomposes, kinins are released. They decrease arterial pressure and are a factor in blood circulation disorder of both organic and reflex origin in the pancreas. The kinins also cause bile to flow into the gland’s ducts, which damages their walls.

Acute pancreatitis may be marked by very severe abdominal pains, persistent vomiting, and collapse. Complications are peritonitis, abscesses, cysts of the gland, and diabetes mellitus. The disease is treated by narcotics, antibiotics, vasoconstrictors, and such antienzyme preparations as trasilol and contrical and by A. V. Vishnevskii’s paranephric novocain blockade. Serious complications are treated surgically.

In chronic pancreatitis, the gland’s external and internal secretions gradually become insufficient. The disease is treated by diet, antispasmodics, substitutes, cholegogues, antibiotics, and antienzyme preparations. During periods of remission, the patient may receive treatment at a health resort.


Shelagurov, A. A. Bolezni podzheludochnoi zhelezy. Moscow, 1970.


References in periodicals archive ?
Autoimmune pancreatitis is a chronic inflammatory disorder of unknown etiology associated with hypergammaglobulinemia that leads to fibrosis and organ dysfunction.
THR-18 for thrombolysis, DP-b99 for acute pancreatitis, and DP-VPA for epilepsy.
Another meta-analysis showed that the adjusted risk of acute pancreatitis was not increased among Danes who had been treated with an incretin drug (Diabetes Care 2015 [doi:10.
2]) and chronic alchohol consumption [5] plus Hypertriglyceridemia as an etiologic factor of acute pancreatitis especially during pregnancy which induced [14].
After a PubMed and Scopus search, we recovered only three cases of hypertriglyceridemic pancreatitis secondary to somatotrophic pituitary adenoma with elevated lipase and amylase (8).
D-Pharm's current clinical programs include DP-b99 for acute severe pancreatitis, THR-18 for acute stroke patients treated with tissue plasminogen activator (tPA) and DP-VPA for epilepsy and bipolar disorder.
Pancreatitis effects hundreds of thousands of people across the world and AC Global Media has decided it is time to produce a free information service for all these sufferers and for those who are interested in the different acute and chronic conditions.
Professor Petersen, said: "The aim of the research was to block excessive calcium entry caused by agents inducing pancreatitis and then test whether this would protect the pancreatic cells from self-digestion and death.
They examined the juice for markers that might distinguish the two disorders, and discovered that the altered gene CD1D, as a single marker, detected 75 percent of patients later diagnosed with pancreatic cancer, but was present in only 9 percent of patients with chronic pancreatitis.
Autoimmune pancreatitis versus pancreatic cancer: a comprehensive review with emphasis on differential diagnosis.
In experiments on mice, the researchers found a number of links between NFAT and acute pancreatitis.