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A growth pattern of epithelial tumors in which the proliferating epithelial cells grow outward from a surface, accompanied by vascularized cores of connective tissue, to form a branching structure.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a benign tumor of man and animals; its basic structural element is a connective-tissue papilla covered with epithelium and containing vessels. The growth of the papillae in various directions sometimes gives a papilloma the appearance of a cauliflower. The presence of numerous papillomas is called papillomatosis. Papillomas are most commonly found on the skin, although they sometimes occur on mucous membranes. In man, they may be congenital or may result from chronic inflammatory irritation. Some papillomas are viral in origin, for example, those of the sexual organs. The recommended therapy is surgical removal.

Papillomatosis in animals is caused by locally specific viruses. It affects cattle, horses, dogs, and rabbits and occasionally goats, sheep, and wild animals. The infection is caused by diseased animals; natural infection results from contact between diseased and healthy animals. The disease is long in duration. Isolated coral-like papillomas appear and then spread. Their surface is dry, horny, and cracked. When injured, papillomas bleed and become infected and ulcerous. Diagnosis is based on clinical and histological examination. Treatment generally consists of surgical removal.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
This would also be the case if it were a papilloma virus, so the next step in my mind would be to attempt surgical excision.
The plethora of histopathological presentations of SP is further complicated by malignant transformation in about 11% of patients of IP, the malignancy can be synchronous or may appear after resection of papilloma (metachronous).
We are reporting a case of solitary endobronchial papilloma with malignant transformation and concomitant TB infection in a middle-aged, nonsmoking Saudi man.
The intraoperative endoscopic image will ultimately verify the extent of the tumor, in most cases allowing for differentiation of the papilloma mass form the surrounding inflammatory lesions [3].
(10) However, we refer to IDPs with foci of architectural and cytologic atypia that quantitatively and qualitatively fail to fulfill criteria for the diagnosis of DCIS as papilloma with atypia or atypical papilloma; this diagnosis is equivalent to that of atypical ductal hyperplasia elsewhere in the breast.
It is believed that cumulative effects of nutritional deficiency, dietary habits, bad oral hygiene, mal-di- rected sharp teeth and infection with human papilloma virus (HPV) is implicated for oral carcinogenesis.
Sinonasal inverted papilloma (IP) or Schneiderian papilloma is a rare benign tumor of the nasal cavities and paranasal sinuses.
Inverted papilloma shows a thickened epithelium bound by an intact basement membrane growing endophytically into the underlying stroma (figure 1).
I hear her grandfather calling to her in his rich Italian voice across the alps: Papilloma. Or, no, not her grandfather.
[p16.sup.INK 4a] and Ki-67 expression in human papilloma virus-related head and neck mucosal lesions.