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A growth pattern of epithelial tumors in which the proliferating epithelial cells grow outward from a surface, accompanied by vascularized cores of connective tissue, to form a branching structure.



a benign tumor of man and animals; its basic structural element is a connective-tissue papilla covered with epithelium and containing vessels. The growth of the papillae in various directions sometimes gives a papilloma the appearance of a cauliflower. The presence of numerous papillomas is called papillomatosis. Papillomas are most commonly found on the skin, although they sometimes occur on mucous membranes. In man, they may be congenital or may result from chronic inflammatory irritation. Some papillomas are viral in origin, for example, those of the sexual organs. The recommended therapy is surgical removal.

Papillomatosis in animals is caused by locally specific viruses. It affects cattle, horses, dogs, and rabbits and occasionally goats, sheep, and wild animals. The infection is caused by diseased animals; natural infection results from contact between diseased and healthy animals. The disease is long in duration. Isolated coral-like papillomas appear and then spread. Their surface is dry, horny, and cracked. When injured, papillomas bleed and become infected and ulcerous. Diagnosis is based on clinical and histological examination. Treatment generally consists of surgical removal.


References in periodicals archive ?
Oncocytic papilloma shows an epithelium composed of tall columnar cells with finely granular eosinophilic cytoplasm.
The diagnosis of squamous papilloma relies on an accurate pathological review.
Based on the previously described findings, the diagnosis of pleomorphic (spindle and squamous cell) carcinoma arising in a mixed glandular and squamous papilloma was rendered.
The investigators reported 100% concordance for at least one human papilloma virus genotype in these 19 pairs, confirming that the virus had been exchanged between the partners; 58% of transmission cases involved HPV-16.
Rarely, a subareolar mass may be palpable with a central solitary papilloma.
Darron Ferris, director of the Gynaecologic Cancer Prevention Centre, at the Medical College of Georgia, in the US, said, 'In most cases women don't know if they have already been exposed to Human Papilloma virus or not.
A:GENITAL warts are caused by the human papilloma virus (HPV) (which also causes warts on your hands or feet).
For instance, since the human papilloma virus (HPV) causes more than 90 percent of cervical cancers, and since the virus is primarily contracted through sexual intercourse, monogamy and practicing safe sex by using condoms can help reduce your risk of contracting the virus in the first place.
New research shows that the human papilloma virus which causes cervical cancer is present in most tongue tumours.
The test for Human Papilloma Virus (HPV) revealed 97% of significant cell abnormalities compared with 76% for a smear.
The test for human papilloma virus revealed 97% of significant cell abnormalities compared with 76% for a smear.