as well as larger verrucous papules
and plaques were noted on the dorsum of hands, shins and feet (Fig 1, 2, 3).
parkeri are not widely available, and an accurate diagnosis is best made by using PCR testing of a biopsy specimen of eschars or papules
. A definitive diagnosis can also be made by using cell culture isolation techniques with the same biopsy specimen, as described for other eschar-associated rickettsioses (12).
The clinical presentation of SESD is usually indistinct, most frequently a papule
or a nodule on the face of adults (1-2, 4, 6, 9, 12).
Significant improvements were also seen with superficial scars (P less than .05) and deep boxcar atrophic scars (P less than .01) on the laser-treated sides of patients' faces, compared with the control sides, but significant improvements were not seen with the number of papules
and nodules or with icepick or rolling scars.
On clinical examination, multiple erythematous papules
and nodules were observed on upper chest, of which some had coalesced to form larger nodules.
The classical or multiple form was first described by Hoffmann and Zurhelle in the year 1921  as groups of multiple, nontender, soft, pedunculated, cerebriform, yellowish or skin-coloured papules
, nodules, or plaques.
are small, solid bumps--the human equivalent of pimples.
Clinically, syringomas appear as small, multiple, firm, skin-colored-to-yellowish papules
, 1 to 3 mm in diameter (2).
For each patient, we received a skin biopsy specimen from the skin papule
, a lymph node biopsy specimen, and paired serum samples.
On day 4, she reported several red papules
on her right hand.
It is reported in books of dermatology (1) that: "papule
is a solid elevated lesion up to 1 cm of diameter".