Paratope | Article about Paratope by The Free Dictionary
epitope (redirected from Paratope)
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epitope: see immunityimmunity,
ability of an organism to resist disease by identifying and destroying foreign substances or organisms. Although all animals have some immune capabilities, little is known about nonmammalian immunity.
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The portion of the antigen molecule that determines its capacity to combine with the specific combining site of its corresponding antibody in an antigen-antibody interaction.
References in periodicals archive
This indicated that the peptides recognized structures in the paratope
that do not participate in antigen binding or that the epitopes were different and mainly determined by the three-dimensional structure of PSA.
As hypothesized in our last report (9), we assume that such a cross-link would occur between some part of E2 outside of the epitope structure and some part of the anti-E2 antibody outside the paratope
structure, such as the sidechains of amino acids.
In a practical sense, it is not be possible to distinguish an idiotope from a paratope
because the binding sites are equivalent.