agonist

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agonist

[′ag·ə‚nist]
(biochemistry)
A chemical substance that can combine with a cell receptor and cause a reaction or create an active site.
(physiology)
A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired.
References in periodicals archive ?
Aripiprazole is a partial agonist of [dopamine.sup.2] receptors and is also associated with partial agonism of 5-[hydroxytryptarnine.sub.1A] receptors and antagonism of 5-[hydroxytryptamine.sub.2A] receptors.
(3) Atypical antipsychotics, except risperidone and paliperidone, are considered to cause less endocrinologie effects than typical antipsychotics through various mechanisms: serotonergic receptor antagonism, fast dissociation from D2 receptors, D2 receptor partial agonism, and preferential binding of D3 vs D2 receptors.
The relative contribution of D3 partial agonism, compared with D2 partial agonism, is a subject of ongoing basic scientific and clinical research.