Pathogenicity


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pathogenicity

[‚path·ə·jə′nis·əd·ē]
(medicine)
The ability of an organism to enter a host and cause disease.

Pathogenicity

 

the ability of a microorganism to cause infectious disease. Pathogenicity varies with the virulence of the infectious agent and with the susceptibility of the infected organisms. Thus for every microbe, it is a relative characteristic that depends on the species, age, sex, and physiological condition of the infected organism.

Pathogenicity develops as a result of a microbial species’ long evolutionary adaptation to the presence of a particular host species. Individual strains from a single microbial species differ in pathogenicity.

References in periodicals archive ?
We report the effectiveness of a whole, inactivated, low pathogenicity H7N9 vaccine against an antigenically distinct, highly pathogenic H7N9 virus in a ferret model.
Lott et al., "Predicting the pathogenicity of novel variants in mitochondrial tRNA with MitoTIP," PLoS Computational Biology, vol.
Pathogenicity of different isolated Fusarium species and their isolates were tested upon healthy nymph and adult whitefly to check mortality.
-90% of the mutants displayed changed phenotypes and/or weakened pathogenicity. There were two types of mutations: Type I is that a gene is disrupted by the T-DNA, which is inserted inside the gene, so that the gene's function is usually lost; Type II is that a gene remains intact in structure, but its function is possibly affected by the T-DNA, which is inserted beside it.
Only the isolates of intermediate pathogenicity had resistance superior to 70% for aminoglycosides, whereas in the isolates from other groups, the resistance did not exceed the rate of 48% for this class of antimicrobial.
The tested strains (VP1 and VR1) were used in experimental infections to confirm pathogenicity. The tested strains were cultured in marine broth in an orbital shaker (120g) at 28[degrees]C for 18 h, allowing each to reach the late exponential growth phase.
UTI: Urinary tract infection; UPEC: Uropathogenic Escherichia coli; Usp: Uropathogenic specific protein; PAI: Pathogenicity island; ORF: Open reading frame; PCR: Polymerase chain reaction.
This evidence suggests that the presence of the IS605 element may have a possible modifying role with respect to strain pathogenicity [4].
[23] via ATMT and several mutants were obtained related to the development and pathogenicity of this fungus.