Paul Greengard


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Greengard, Paul,

1925–, American neuroscientist, b. New York City, Ph.D. Johns Hopkins, 1953. Greengard was on the staff at Geigy Research Laboratories (1959–67) and a professor at the Albert Einstein College of Medicine (1961–70) and Yale (1968–83). In 1983 he became a professor at Rockefeller Univ. Greengard shared the 2000 Nobel Prize in Physiology or Medicine with Arvid CarlssonCarlsson, Arvid,
1923–, Swedish pharmacologist, grad. Univ. of Lund, Sweden, (M.D., Ph.D., 1951). Carlsson was a professor at the Univ. of Lund (1951–59) and at the Univ. of Gothenburg, Sweden (1959–89).
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 and Eric KandelKandel, Eric Richard,
1929–, American neurobiologist, b., Vienna, Austria, M.D. New York Univ., 1956. Kandel was at the Harvard Medical School (1960–65) and New York Univ. (1965–74) before joining the faculty at Columbia in 1974.
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 for their discoveries concerning signal transduction in the nervous system. Greengard's contribution to the work was his discovery of the mechanism by which dopaminedopamine
, one of the intermediate substances in the biosynthesis of epinephrine and norepinephrine. See catecholamine.
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 and several other neurotransmittersneurotransmitter,
chemical that transmits information across the junction (synapse) that separates one nerve cell (neuron) from another nerve cell or a muscle. Neurotransmitters are stored in the nerve cell's bulbous end (axon).
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 carry messages between nerve cells. His findings contributed to an improved understanding of how several drugs work in the body.
References in periodicals archive ?
Paul Greengard, recipient of multiple awards and honors throughout his career, and includes a research team of world-renowned scientists.
To find out if this process is influenced by microRNAs, a team led by Anne Schaefer and Paul Greengard at Rockefeller University offered cocaine to mice whose neurons lack Ago2, a protein essential for the production and function of certain microRNAs.
Paul Greengard and colleagues report in the 10 December 2009 issue of Neuron that improper functioning of the protein complex GLP/G9a is linked in mice to a mental retardation-like effect known as 9q34 syndrome.
Paul Greengard, who won the Nobel Prize for work discovering the brain mechanisms involved in Parkinson's disease, said the research cited in the report 'makes it a very reasonable possibility that this Gulf War illness is not attributable simply to stress of troops that were deployed'.
Paul Greengard of New York's Rockefeller University, Eric Kandel of Columbia University, also in New York, and Swede Arvid Carlsson, formerly of the University of Gothenburg, share the nearly $1 million award, announced by Sweden's Karotinska Institute.
Kandel of Columbia University, and Paul Greengard of Rockefeller University in New York City.
The Pearl Meister Greengard Prize was founded in 2004 by Nobel laureate Paul Greengard, Vincent Astor Professor and head of the Laboratory of Molecular and Cellular Neuroscience at Rockefeller University, and his wife, sculptor Ursula von Rydingsvard.
Swede Arvid Carlsson and Americans, Paul Greengard and Eric Kandel will share the pounds 625,000 prize for their pioneering discoveries concerning the way brain cells send messages to each other, called 'slow synaptic transmission.
Paul Greengard leads its research team of more than 50 world-renowned scientists.
Nobel Laureate and National Academy of Sciences member Paul Greengard, Ph.
Nobel Laureate Paul Greengard, who is Vincent Astor Professor and head of the Laboratory of Molecular and Cellular Neuroscience at The Rockefeller University, founded the Pearl Meister Greengard Prize in 2003, along with his wife, sculptor Ursula von Rydingsvard.