Paul Greengard


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Greengard, Paul,

1925–, American neuroscientist, b. New York City, Ph.D. Johns Hopkins, 1953. Greengard was on the staff at Geigy Research Laboratories (1959–67) and a professor at the Albert Einstein College of Medicine (1961–70) and Yale (1968–83). In 1983 he became a professor at Rockefeller Univ. Greengard shared the 2000 Nobel Prize in Physiology or Medicine with Arvid CarlssonCarlsson, Arvid,
1923–, Swedish pharmacologist, grad. Univ. of Lund, Sweden, (M.D., Ph.D., 1951). Carlsson was a professor at the Univ. of Lund (1951–59) and at the Univ. of Gothenburg, Sweden (1959–89).
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 and Eric KandelKandel, Eric Richard,
1929–, American neurobiologist, b., Vienna, Austria, M.D. New York Univ., 1956. Kandel was at the Harvard Medical School (1960–65) and New York Univ. (1965–74) before joining the faculty at Columbia in 1974.
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 for their discoveries concerning signal transduction in the nervous system. Greengard's contribution to the work was his discovery of the mechanism by which dopaminedopamine
, one of the intermediate substances in the biosynthesis of epinephrine and norepinephrine. See catecholamine.
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 and several other neurotransmittersneurotransmitter,
chemical that transmits information across the junction (synapse) that separates one nerve cell (neuron) from another nerve cell or a muscle. Neurotransmitters are stored in the nerve cell's bulbous end (axon).
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 carry messages between nerve cells. His findings contributed to an improved understanding of how several drugs work in the body.
References in periodicals archive ?
Lucian Medrihan, a research associate in the lab of neuroscientist and Nobel laureate Paul Greengard who led the study, said: "While existing SSRIs can produce moderate effects within hours or even minutes, most people don't really begin to feel better until they've been on the drugs for a significant amount of time-a major drawback when it comes to treating clinical depression.
Paul Greengard, born in 1925 and a 2000 Nobel laureate in medicine, still works on average six days a week, from 9 A.
Paul Greengard of the Rockefeller University in New York led the 2006 study, in which he and his team worked on mice that lacked p11.
Jupiter, Florida-based Envoy, which was founded in 2009, is owned by 5AM Ventures, Roche Venture Fund, the founders Nathaniel Heintz, Paul Greengard, Brad Margus and Jeffrey Friedman, and Takeda Ventures Inc, Takedaa[euro](tm)s corporate venture arm holding some 12.
To find out if this process is influenced by microRNAs, a team led by Anne Schaefer and Paul Greengard at Rockefeller University offered cocaine to mice whose neurons lack Ago2, a protein essential for the production and function of certain microRNAs.
Paul Greengard and colleagues report in the 10 December 2009 issue of Neuron that improper functioning of the protein complex GLP/G9a is linked in mice to a mental retardation-like effect known as 9q34 syndrome.
Paul Greengard, house families visiting hospitalized military personnel, and convert the scrapped aircraft carrier USS Intrepid into a floating military museum.
Paul Greengard, who won the Nobel Prize for work discovering the brain mechanisms involved in Parkinson's disease, said the research cited in the report 'makes it a very reasonable possibility that this Gulf War illness is not attributable simply to stress of troops that were deployed'.
I'm also pleased to be able to count two of the year 2000's Nobel Prize winners as members of the MBL family: Paul Greengard of Rockefeller University, an alumnus of the Embryology Course and a former faculty member of the Neurobiology Course, and Eric Kandel of Columbia, a past MBL investigator and Corporation Member.
Paul Greengard of New York's Rockefeller University, Eric Kandel of Columbia University, also in New York, and Swede Arvid Carlsson, formerly of the University of Gothenburg, share the nearly $1 million award, announced by Sweden's Karotinska Institute.
El sueco Arvid Carlsson y los estadunidenses Paul Greengard y Eric Kandel obtuvieron el Premio Nobel de Fisiologia y Medecina por sus investigaciones pioneras sobre la transmision de senales en el sistema nervioso.