acetaminophen

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acetaminophen

(əsēt'əmĭn`əfĭn), an analgesicanalgesic
, any of a diverse group of drugs used to relieve pain. Analgesic drugs include the nonsteroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, acetaminophen, narcotic drugs such as morphine, and synthetic drugs with morphinelike action such as meperidine
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 and fever-reducing medicine. It is an active ingredient in many over-the-counter medicines, including Tylenol and Midol. Introduced in the early 1900s, acetaminophen is a coal tar derivative that acts by interfering with the synthesis of prostaglandinsprostaglandin
, any of a group of about a dozen compounds synthesized from fatty acids in mammals as well as in lower animals. Prostaglandins are highly potent substances that are not stored but are produced as needed by cell membranes in virtually every body tissue.
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 and other substances necessary for the transmission of pain impulses. Although its action is similar to that of aspirinaspirin,
acetyl derivative of salicylic acid (see salicylate) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic fever and
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, it lacks aspirin's anti-inflammatory and blood-thinning effects, is less irritating to the stomach, and can be used by people who are allergic to aspirin. Heavy use, however, has been linked to an increased incidence of liver failure, especially in heavy drinkers of alcoholic beverages and in those who are not eating enough, and overdose, especially in children, can be fatal.

acetaminophen

[ə‚sēd·ə′mēn·ə·fən]
(organic chemistry)
C8H9O2N Large monoclinic prisms with a melting point of 169-170°C; soluble in organic solvents such as methanol and ethanol; used in the manufacture of azo dyes and photographic chemicals, and as an analgesic and antipyretic.
References in periodicals archive ?
Unfortunately, this Pediatrix Group that the hospital has contracted with chose to remove him from the medical directorship based on anonymous complaints and complaints from hospital middle management," Krishna said.
Hospital board member Berna Mayer said having a contract with Pediatrix puts the hospital in a position to receive state funding for disabled children.
Pediatrix used its cash to complete the acquisition of Pediatric Cardiology Associates, and the transaction is expected to contribute to Pediatrix's earnings.
The neonatologists practicing at Baptist Hospital also expect that as part of Pediatrix they'll have more comprehensive information to help them continuously improve clinical quality.
Working with Pediatrix and the physicians here in Seattle, I expect that we'll be able to expand on important diagnostic initiatives in maternal-fetal care.