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Related to Peptidase: signal peptidase


An enzyme that catalyzes the hydrolysis of peptides to amino acids.



any one of a group of enzymes of the hydrolase class. Peptidases split off one amino acid at a time from either the carboxylic or the aminic end of protein and peptide molecules. Accordingly, they are classed as either carboxypeptidases or aminopeptidases. Dipeptidases hydrolyze dipeptides.

References in periodicals archive ?
These genes code for peptidases, which normally chew up proteins (polypeptides) and lack the ability to recognize anything else.
1) name of item: purchase of collagen peptidase 100% with carbohydrate 2gm, calcium 20mg, iron 1 mg with sodium 0.
These include dipeptidyl peptidase inhibitors (DPP4i) and statins.
The KLK8 peptidase is present in numerous human tissues (10) and is involved in several physiological and pathologic processes (11, 12).
Coverage includes salivary biomarkers, tumor markers in pseudopodia for invasive migration, intraocular lymphoma markers, serum tumor markers in breast cancer, diagnostic classification using gene expression profiling in AML, tumor antigens as markers of minimal residual disease in acute myeloid leukemia, activity and expression of dipeptidyl peptidase IV and cathepsin H in human cutaneous melanoma compared to other common cancers, ovarian cancer detection, comparison of the prognostic association of nucleolar size between uveal and conjunctival melanoma, biomarkers of hepatocellular carcinoma, cell adhesive markers in metastasizing colorectal carcinoma, and fetal hemoglobin as an oncofetal marker.
Tokyo, Japan, July 14, 2005 - (JCNN) - Takeda Pharmaceutical (TSE: 4502) announced on July 14 that it has agreed with Pharmaceutical Product Development (PPD), a US pharmaceutical company, concerning rights to the dipeptidyl peptidase IV (DPP4) inhibitor
Additionally, LINCL is caused by mutations in the Cln2 gene that leads to the deficiency and/or loss of function of Tripeptidyl Peptidase 1 (TPP1) that leads to accumulation of autofluorescent storage materials in neurons and in other cells.
The oral drugs being developed for use in diabetes care include the dipeptidyl peptidase 4 inhibitors (DPP4i) omarigliptin and trelagliptin.
Topics of the ten papers include the biodistribution of metal ions, medicinal inorganic chemistry, the chemical toxicology of metals and metalloids, charge transport in biological molecules, bioorganometallic chemistry, interactions with metal ions, the bioorganic side of nucleic acid chemistry, nuclease and peptidase models, metalloporphyrins and metalloporphyrinoids, model complexes for enzymes containing vanadium, model complexes for enzymes containing molydbenum and tungsten, structural and functional models for oxygen-activated nonheme iron enzymes, model chemistry of iron-sulfur protein active sites and model complexes of enzymes containing nickel.