Perfusion


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

perfusion

[pər′fyü·zhən]
(physiology)
The pumping of a fluid through a tissue or organ by way of an artery.

Perfusion

 

a method of passing physiological solutions, blood, blood substitutes, or other fluids through the blood vessels of an organ, a part of the body, or the entire body. Perfusion may be performed on organs completely removed from the body or on organs within the body but isolated from the general vascular system. Widely used in experimental physiology, it permits preservation of the vital activities of organs for a certain period, enabling the study of organ functions and of the effect of hormones, mediators, enzymes, and medicinal substances on physiological systems and the entire body. The method is used in various branches of surgery, including transplantation of organs and tissues. Perfusion of the entire body is used, for example, during heart surgery.

The term “perfusion” also designates the supplying of blood to organs of the body under natural conditions (for example, perfusion of the kidneys, brain, or other organs), which is determined by the state of cardiac activity and local vascular tonus.

References in periodicals archive ?
XVIVO Perfusion AB nominating committee members for the 2018 Annual General Meeting are Henrik Blomquist, of Bure Equity; Martin Lewin, of Eccenovo AB and Joachim Spetz, of Swedbank Robur.
In normal LAD group 2 patients have normal myocardial perfusion scan; while rest of the 4 exhibit mild to moderate intensity fixed perfusion defects involving distal anteroseptal and distal inferoseptal walls.
CT perfusion is helpful in differentiating thymoma from non-thymoma malignancies including lymphoma, thymic carcinoma, and invasive lung cancer involving the anterior mediastinum.
Myocardial perfusion PET is a robust nuclear cardiology test that supports the Centers for Medicare and Medicaid Services' initiatives to improve the quality and efficiency of healthcare while controlling costs.
Cases with space occupying lesion at initial NCCT, cerebellar or brainstem infarction, infarction outside the perfusion CT coverage area, age of less than 18 years, pregnancy or contraindications for contrast agent administration were not included.
Dynamic susceptibility contrast imaging, an MRI perfusion technique, is the most commonly used protocol in clinical practice.
By far the most benefits and greatest savings with continuous operation and perfusion are experienced with commercial manufacturing.
The system's flexibility allows the user to choose both the ventilation and perfusion strategy in accordance with the clinic's desired protocol.
Bone perfusion by DCE-MRI can be assessed by semi-quantitative method [10-14] and pharmacokinetic model [1518].
With this in mind, TAP Biosystems, a supplier of cell culture and consumables for life science, announced a new application of its ambr micro bioreactor system as a perfusion mimic, enabling scientists to rapidly and easily develop large scale perfusion culture processes of unstable, low producing or minimally expressing proteins or antibodies.
The application of ambr as a semi-continuous chemostat model will save scientists valuable time with media and process development, enabling them to rapidly scale up an optimum perfusion culture process for increased protein yields," said Barney Zoro, ambr product manager.
Clinical Perfusion MRI provides the more recent advances in perfusion magnetic resonance imaging (MRI), while providing excellent information on the theoretical and experimental aspects.