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The pumping of a fluid through a tissue or organ by way of an artery.



a method of passing physiological solutions, blood, blood substitutes, or other fluids through the blood vessels of an organ, a part of the body, or the entire body. Perfusion may be performed on organs completely removed from the body or on organs within the body but isolated from the general vascular system. Widely used in experimental physiology, it permits preservation of the vital activities of organs for a certain period, enabling the study of organ functions and of the effect of hormones, mediators, enzymes, and medicinal substances on physiological systems and the entire body. The method is used in various branches of surgery, including transplantation of organs and tissues. Perfusion of the entire body is used, for example, during heart surgery.

The term “perfusion” also designates the supplying of blood to organs of the body under natural conditions (for example, perfusion of the kidneys, brain, or other organs), which is determined by the state of cardiac activity and local vascular tonus.

References in periodicals archive ?
Two of the cerebrovascular parameters that are changed during tracheal suction are intracranial pressure (ICP) and cerebral perfusion pressure (CPP) (Gemma et al.
The isolated rat hearts in Langendorff system were perfused for 10 min under perfusion pressure of 65 mm Hg to establish a baseline of CPF, and then the perfusion was conducted with low flow at 20 mm Hg for 40 min to induce global ischemia in the heart tissues.
So, in this study we aimed to investigate the possible effects of PAMP and calcitonin forms on perfusion pressure, heart rate and contractile force in isolated perfused rat hearts.
In addition, cardiac failure and metabolic acidosis can be aggravated or precipitated by the frequent use of vasopressors needed to maintain an acceptable cerebral perfusion pressure.
The definition of a secondary insult was intracranial pressure > 20 mm Hg, cerebral perfusion pressure < 60 mm Hg and systolic blood pressure < 100 mm Hg for 5 minutes or more in a 10-minute period starting from when the nursing intervention began.
The issue of intracranial pressure monitoring and maintenance of cerebral perfusion pressure with regard to traumatic brain injury was described by Figaji in the March 2010 edition of CME.
In the vascular theory, low blood pressure, particularly when combined with elevated IOP, can reduce the perfusion pressure at the optic nerve head.
Within 48 hours of the injury, he developed poor peripheral perfusion and a distended abdomen; the intravesical pressure was 32 mmHg and the abdominal perfusion pressure 23 mmHg.
Like cerebral perfusion pressure, which is the mean arterial pressure (MAP) minus the intracranial pressure, abdominal perfusion pressure (APP) is the MAP--IAP and has been proposed as a more accurate predictor of visceral perfusion and a possible end-point for resuscitation.
The perfusion pressure was constantly monitored by measuring the water pressure.