Perfusion

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perfusion

[pər′fyü·zhən]
(physiology)
The pumping of a fluid through a tissue or organ by way of an artery.

Perfusion

 

a method of passing physiological solutions, blood, blood substitutes, or other fluids through the blood vessels of an organ, a part of the body, or the entire body. Perfusion may be performed on organs completely removed from the body or on organs within the body but isolated from the general vascular system. Widely used in experimental physiology, it permits preservation of the vital activities of organs for a certain period, enabling the study of organ functions and of the effect of hormones, mediators, enzymes, and medicinal substances on physiological systems and the entire body. The method is used in various branches of surgery, including transplantation of organs and tissues. Perfusion of the entire body is used, for example, during heart surgery.

The term “perfusion” also designates the supplying of blood to organs of the body under natural conditions (for example, perfusion of the kidneys, brain, or other organs), which is determined by the state of cardiac activity and local vascular tonus.

References in periodicals archive ?
Although OPP was reduced, autoregulation might maintain blood flow despite changes in perfusion pressure in young adults.
Studies in patients with cardiac arrest outside hospital have consistently found that epinephrine increases aortic relaxation pressure and increases coronary perfusion pressure, increasing the chances of achieving ROSC.
The Ang II infusion induced increases in coronary perfusion pressure in a concentration-dependent fashion in all experimental groups (Figure 3(a)).
7 mL/100 mL/min each year, while it was not correlated with perfusion pressure, arterial pressure, or intraocular pressure.
Two of the cerebrovascular parameters that are changed during tracheal suction are intracranial pressure (ICP) and cerebral perfusion pressure (CPP) (Gemma et al.
Changes in occipital capillary perfusion pressures during coronary artery bypass graft surgery.
Vascular markers, such as systolic and diastolic systemic arterial blood pressure, ocular perfusion pressures, systolic and diastolic ocular perfusion pressure, were estimated according to the formulae [15]:
9% of patients with some kind of pain, ranked at stages II, III and IV of Manchester protocol (22), and the sum of these symptoms may both increase blood pressure, as the ICR determining changes in cerebral perfusion pressure.
Hypertension, perfusion pressure and primary open-angle glaucoma.
As discussed in pathogenesis the key to management of a head injured patient with cerebral edema or diffuse axonal injury is to maintain cerebral perfusion pressure by control of ICP and hemodynamic status.
Tissue perfusion is proportional to the difference between the interstitial fluid pressure and the capillary perfusion pressure.
After 24 hours of the initial procedures, which included the evaluation of the intraocular pressure (IOP), basal mean arterial pressure (MAP), ocular perfusion pressure (PPO), ultrasonography and fluorescein angiography, the treatment protocols were initiated with sildenafil or placebo.