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Related to Perlèche: cheilosis, intertrigo


An inflammatory condition occurring at the angles of the mouth with resultant fissuring.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



fissures in the corners of the mouth. Certain microorganisms (streptococci, staphylococci, yeastlike fungi) and vitamin deficiency cause and prolong perlèche. Perlèche may also originate as an allergy, caused by taking certain drugs or by using plastic prostheses, toothpaste, or lipstick. A honey-colored or whitish crust often forms on the perleche, and the skin surrounding the lesion becomes red and edematous. Upon determining the precise cause treatment includes the use of antimicrobial and antifungal preparations, hormones (corticosteroids), vitamins, and ultraviolet irradiation.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.