Peyer's patches


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Peyer's patches

[′pī·ərz ‚pach·əz]
(histology)
Aggregates of lymph nodules beneath the epithelium of the ileum.
References in periodicals archive ?
Antigen-induced, tolerogenic CD11c+, CD11b+ dendritic cells are abundant in Peyer's patches during the induction of oral tolerance to type II collagen and suppress experimental collagen-induced arthritis.
By ISH analysis, abundant cytoplasmic viral nucleic acid was detected in macrophages within germinal centers and subcapsular and medullary sinuses of the mesenteric lymph nodes from all 4 dogs (Figure 2, panel H), mandibular lymph nodes from 2 dogs, ileal Peyer's patches from all 4 dogs (Figures 2, panels D, F), ellipsoids (terminal arterioles) of the spleen for 1 dog, and germinal centers in splenic white pulp for 2 dogs.
Oral intake of small amounts of glycosylated UC-II presents active epitopes, with the correct three-dimensional structures, to Peyer's patches, which influences the signaling required for the development of immune tolerance.
The IgA receptor has been found to be located on M cells of Peyer's patches in the human intestine, and the receptor contributes to the uptake of antigen-IgA immune complexes into Peyer's patches (Mantis et al.
However, in the case of nanoparticles the absorption of nanoparticles takes place via Peyer's patches region, reaches lymphatic system, bypasses the first pass metabolism (bypasses liver: degradation of insulin is significantly reduced) and particles will be degraded and delivers the insulin in the blood stream.
In contrast to the peptide hormone delivery vehicles, however, the Macromune formulation is designed to gain preferential access to the M cells of the Peyer's patches located in the lower small intestine and is thus able to interact with the mucosal immune system and stimulate either a local or a systemic immune response to incorporated antigens.
Since 70% of our immune system emanates from the bowel and Peyer's patches (Figure 2) make 90% of our T lymphocytes, it is important to prepare the soil with care.
The percentage of Fas-receptor (Fas+) and Fas-ligand positive (FasL+) lymphocytes was enhanced in Peyer's patches after exercise.