Peyronie's disease


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Peyronie's disease

[¦pā·rə¦nēz di‚zēz]
(medicine)
Scarring of the shaft of the penis; may interfere with normal erections.
References in periodicals archive ?
"We hope that through this initiative, more men with signs of Peyronie's disease or other sexual health conditions will start a conversation with a urologist."
"We are hoping to start a clinical trial in men with Peyronie's disease to test the combination of these two drugs in the near future.
Treatment for structural penile disease depends upon the nature and nature and severity of diseases in case of Peyronie's disease. Medical treatment in early stages and surgical in mature calcified stage.
The study found that men with Peyronie's disease were 43 percent more likely to be struck down with stomach cancer, 39 percent more likely to develop testicular cancer and 19 percent more likely to get skin cancer (melanoma), compared to men with no penis complaints.
Peyronie's disease, which is caused by a buildup of scar tissue under the skin of the penis, causes painful erections and an increased curvature of the male reproductive organ.
Pathophysiology and management of Peyronie's disease in adult patients: An update.
Free Radicals and Oxidative and Nitrosative Stress as Fundamental Component of Peyronie's Disease. In the last fifteen years, oxidative stress has been shown to play a decisive role in the physiopathological mechanisms of PD [6, 22, 26, 30, 32, 34, 35, 39].
Peyronie's disease is caused by a buildup of collagen, known as a plaque, in the penis.
Now, at the start of Men's Health Week, a charity believe it is time to begin talking about Peyronie's disease.
Almost none of the men could recall being informed about loss of penile length, and none were aware of the potential for Peyronie's disease. Overall, men who have undergone radical prostatectomy "have largely unrealistic expectations about their postoperative sexual function," the researchers concluded.
Swedish Orphan Biovitrum AB (publ) (Sobi) has received approval from Swissmedic, the Swiss Agency for Therapeutic Products, for Xiapex (collagenase clostridium histolyticum) for the treatment of adult men with Peyronie's disease. The indication is for patients with a palpable plaque and curvature deformity of at least 30 degrees at the start of therapy.
The use of Tutoplast(R) was first described by a study in the surgical management of the Peyronie's disease.10 After that Tutoplast(R) has been described in penile surgeries by other authors.1112 However we could not find any publications that demonstrate its use to repair the defect of tunica albuginea of testis.