, on the other hand, is beginning to have clinical utility.
offers great hope in circumventing a major barrier to successful drug development.
research includes studying the genes and proteins that play essential roles in drug responses.
The NPSC examined in detail three mock submissions that addressed different uses of pharmacogenomics
data during drug development.
In many respects, nutrigenomics parallels the development of pharmacogenomics
. As with pharmaceuticals, a number of key enzymes and metabolic reactions are involved with the digestion, absorption and metabolism of food.
may finally solve the clinical puzzle of multidrug resistance and/or why an estimated 15%20% of people with epilepsy are refractory to all antiepileptic drugs.
Genomics' technology will enable faster, more cost-effective access to genomic information that is needed for drug discovery, pharmacogenomics
, and diagnostics.
has been compared in significance to the discovery of antibiotics, and its benefits will be widespread as drug therapy continues to be the primary weapon against disease (Scheuerle, 2001).
NaPro BioTherapeutics, Inc., headquartered in Boulder, Colorado, is a biopharmaceutical company focused on the development, production and licensing of complex natural-product pharmaceuticals as well as the development and licensing of novel genetic technologies for applications in human therapeutics and diagnostics, pharmacogenomics
* Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics
: The Continuing Evolution of Pharmacologic Issues in HIV Disease, by Stephen Becker, M.D.
will help drug companies by identifying the populations likely to suffer side effects from a given therapy, thus averting the kind of panic that can undermine an effective drug in which vast sums of money have been invested.
This report describes the latest concepts of development of personalized medicine based on pharmacogenomics
, pharmacogenetics, pharmacoproteomics, and metabolomics.