The ministry said aspirin and acetaminophen may be used as substitutes for phenacetin
as they pose a far smaller risk of side effects even if used over the long term.
Statistics indicate that this hypertension apparently accounted for about half" of the nonfatal heart disease effects seen among the phenacetin
users, says the study's biostatistician, Bernard Rosner of Harvard Medical School in Boston.
"I didn't know what Phenacetin
was and it caused me some difficulty.
Drug traffickers have continued to use the aforementioned chemicals in addition to activated carbon and phenacetin
. Traffickers use activated carbon to deodorize and discolor water and other liquids and phenacetin
, a highly toxic analgesic, to increase volume of cocaine.
CYP1A2 activity was assessed by formation of paracetamol from phenacetin
by the method reported previously (Wang et al.
They made an APC - aspirin, phenacetin
, caffeine - powder as relief for colds, flu, arthritis and nerve pains.
A shipment of industrial rollers was employed to hide cocaine, cannabis and the potentially deadly cutting agent phenacetin
Common mixers include talcum powder or washing detergent but also other, often very dangerous drugs such as benzocaine (a local anaesthetic which makes your mouth go numb), phenacetin
(used as a painkiller until it was linked with cancer), nannitol (artificial sweetener that can act as a laxative) and even chemicals found in horse tranquillisers or dog-worming pills.
(148) This entity, which is characterized by long-term usage of analgesic medications and the presence of interstitial inflammation with significant tubulointerstitial scarring, is now uncommon because of the withdrawal of phenacetin
as a therapeutic agent.
Compound analgesics consisting of phenacetin
, aspirin and caffeine became popular and analgesic nephropathy was born.
Several agents like nitrates, nitrites, aniline, phenacetin
, sulphonamides, nitrobenzene etc.
There are several drugs and toxic agents that can oxidize hemoglobin to methemoglobin, such as nitrates, chlorates, quinones, phenacetin
, sulfonamides, aniline dyes, and local anesthetics such as procaine, benzocaine, and lidocaine (115).