Phosphatidyl Serine

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Phosphatidyl Serine

 

any of the natural organic compounds of the phospholipid group. Phosphatidyl serines are formed from residues of glycerin, fatty acids, phosphoric acid, and the amino acid serine. They are components of biological membranes and are present in significant quantities in nerve tissue. Phosphatidyl serines are synthesized in the liver (seeCEPHALINS and LIPIDS).

References in periodicals archive ?
Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia.
Secondly, ANXA5, which is associated with the phosphatidylserine, flips to the outer membrane leaflet, resulting in uncoupling of [BK.
Externalization of phosphatidylserine of HT-29 and T84 cells treated with the indicated compounds for 48 h was determined by staining with Annexin-V-FLUOS and propidium iodide using the Annexin-V-FLUOS Staining Kit (Roche Diagnostics, Mannheim, Germany) and subsequent flow cytometry (Accuri C6, BD Biosciences, Heidelberg, Germany) according to the manufacturer's instructions.
Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.
Phosphatidylserine exposure and red cell viability in red cell aging and in hemolytic anemia.
Detection of phosphatidylserine externalization and mode of cell death
This procedure was employed to target apoptotic cells that express phosphatidylserine (PS) on the outer leaflet of the plasma membrane.
Objective: We aimed to detect novel in vitro effects of clopidogrel on platelets by assessment of the following parameters: malondialdehyde, glutathione, nitrite, aggregation response, and expressions of P-selectin, fibrinogen, apolipoprotein Al, apolipoprotein B, and phosphatidylserine.
Describing themselves as the "natural brain vitamin" company, Lipogen Ltd produces specialty phospholipids, including phosphatidylserine (PS), a natural phospholipid that improves brain function, and PS-Plus (PS plus PA), a natural functional ingredient that alleviates mental and psychological stress effects (such as decreasing cortisol levels).
In addition, he's created a combination of specific brain supporting nutrients, including acetyl-L-carnitine, alpha lipoic acid, coenzyme Q10, n-acetyl-cysteine, and phosphatidylserine.
Annexin V assay: Detection of flipping of phosphatidylserine was done by annexin V assay by using a commercially available TACS[TM] Annexin V-FITC Apoptosis Detection kit (R & D, USA) (20).

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