Piperazine


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piperazine

[pī′par·ə‚zēn]
(organic chemistry)
C4H10N2 A cyclic compound; colorless, deliquescent crystals, melting at 104-107°C; soluble in water, alcohol, glycerol, and glycols; absorbs carbon dioxide from air; used in medicine.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Piperazine

 

(or diethylenediimine), a heterocyclic compound; colorless crystals. Melting point, 104°C; boiling point, 145°-146°C. Poorly soluble in water and ether; readily soluble in alcohol.

Piperazine is a strong base. It is obtained by hydrogenation of pyrazine or 2,5-piperazinedione or condensation of dibromo-ethane with ammonia. Piperazine and its derivatives are used in analytical chemistry for microcrystalloscopic identification of Mo, V, and W and in medicine (in the form of salts of adipinic, citric, phosphoric, or sulfuric acid) as an anthelmintic in cases of ascariasis and enterobiasis.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.
Piperazine, which includes benzylpiperazine, a central nervous system stimulant, has been added as a Schedule V drug, with seven of its varieties.
The piperazine derivatives, a class of amphetamine-like compounds that includes BZP (benzylpiperazine) and TFMPP (trifluoromethylphenylpiperazine) are making a comeback as "legal ecstasy." Often perceived as safe by the public, adverse effects may range from minimal to life-threatening.
Piperazine designer drugs--"party pills"--are synthetic chemical compounds.
Now you might reasonably expect that this would successfully worm cats but a quick read of the label proved it only contains piperazine.
Halazy, "3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome C release via bax channel modulation," Journal of Medicinal Chemistry, vol.
(iii) another peak at [delta] 2.4 (shift from 2.6 to 2.4) in Cipro@C-dots indicates formation of bonds between piperazine moiety of ciprofloxacin and C-dots;