Among heterocyclic compounds, Piperidine
has played significant role in drug discovery process .
Zhang et al., "Heteroaromatic and aniline derivatives of piperidines
as potent ligands for vesicular acetylcholine transporter," Journal of Medicinal Chemistry, vol.
michiganensis In vitro and the application of piperidine
alkaloids to manage symptom development of bacterial canker on tomato in the greenhouse.
Figure 1 demonstrates the load and displacement curves for the epoxy and particle/epoxy systems with the piperidine
curing agent, which shows the same tendency of load-displacement curves for different types of particles.
The Pipe and Kim research groups devised a way to strongly link long polymer chains of a plastic called polyacrylic acid (PAA) with short strands of another called polyacryloyl piperidine
The reactive hindered piperidine
amine, N,N'-bis(2,2,6,6-tetramethyl-4piperi dinyl)--1,6-hexanediamine (HDM) was kindly supplied by Evonik Tianda Chemical Additive Co.
4-t-butyl cyclohexanone, piperidine
, paraformaldehyde, acetic acid, hydroxyl amine hydrochloride, sodium acetate, sodium bisulfite, potassium cyanide, diethyl ether and other chemicals were purchased from Merck chemical Co.
In search of other opioids with good analgesic potency and fewer incidence of side effects mainly respiratory depression, a phenyl piperidine
derivative fentanyl and thienyl analogue of fentanyl-Sufentanil and many more were discovered and studied.
Fragmentation of the precursor ion at m/z 306.12 [[M+H].sup.+] showed a loss of 17 Da, forming the production of m/z 288 presumably due to the loss of OH group at piperidine
p-Tolualdehyde, sebacoyl chloride, 1,6-hexanediol, DMAP, triethylamine, DMF, and piperidine
(Aldrich) were used as received.
This assignment leans on the earlier studies of amino acids lyophilized and deposited onto the colloidal Au surface [27, 28], BK, and its modified analogs [16-18], piperidine
(Pip) [29,30] andthiophene (Thi) [31-33].