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Related to Pituitary failure: hypopituitarism, pituitary dysfunction


Condition caused by insufficient secretion of pituitary hormones, especially of the adenohypophysis. Also known as panhypopituitarism.



a chronic condition caused by reduced internal secretion of the pituitary body.

Hypopituitarism is manifested by insufficiency of function of the thyroid, adrenal cortex, and gonads. Trauma, tumors, infections, and hemorrhages in the area of the base of the brain can result in hypopituitarism. Hypopituitarism is manifested in arrested growth (nanism), impairment of lipometabolism, causing obesity or severe emaciation (cachexia), or underdevelopment of the sexual organs. In women with hypopituitarism, menstruation ceases and the uterus, ovaries, and mammary glands atrophy. In men the testicles and penis atrophy. Physical and mental languor, frequent dizziness, buzzing in the ears, headaches, sleepiness, susceptibility to fatigue, and a lowering of the basal metabolism are characteristic of hypopituitarism. Pituitary tumors are treated by X-ray and radiotherapy or surgical operation; other forms are treated by hormonal therapy.


References in periodicals archive ?
In patients with pituitary tumors, pituitary failure may develop with the effect of adenoma itself or following surgical excision.
It usually unfolds as complete anterior pituitary failure, but some of the functions may be preserved.
However, the day-to-day reality of having to take medication has taken its toll on Russell and his specialist Dr Tara Kearney reveals that Russell''s pituitary failure means he no longer produces the hormone cortisol -and the consequences could potentially be fatal.