dendritic cell

(redirected from Plasmacytoid dendritic cells)
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dendritic cell

[den′drid·ik ¦sel]
(cell and molecular biology)
A specialized cell of the lymphoid reticuloendothelial system that presents antigens for detection by lymphocytes.
References in periodicals archive ?
Patients with chronic hepatitis B infection display deficiency of plasmacytoid dendritic cells with reduced expression of TLR9.
Productive infection of plasmacytoid dendritic cells with human immunodeficiency virus type 1 is triggered by CD40 ligation.
Plasmacytoid dendritic cells (natural interferon- a/p-producing cells) accumulate in cutaneous lupus erythematosus lesions.
Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6.
12) Plasmacytoid dendritic cells express neither histiocytic markers nor myeloperoxidase.
These steroid treatments work by killing certain immune system cells, including plasmacytoid dendritic cells (PDCs) that overproduce type 1 interferons, an immune system substance that contributes to lupus and other autoimmune diseases.
Large amounts of type I IFN are produced by plasmacytoid dendritic cells (pDCs) upon engagement of the pattern recognition receptor TLR7.
In the studies, these IMO compounds activated plasmacytoid dendritic cells to produce IFN-alpha and also activated B cells.
Through TLR9, CPG 7909 directly and selectively activates plasmacytoid dendritic cells and B cells, which can then utilize the tumor's own antigens to fight immune tolerance to malignant cells and drive specific anti-tumor responses through the production of antigen specific cytotoxic T cells (CTLs) and antibodies.