Plasmalogen


Also found in: Medical, Wikipedia.

plasmalogen

[plaz′mal·ə·jən]
(biochemistry)
Any of a group of glycerol-based phospholipids in which a fatty acid group is replaced by a fatty aldehyde.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Plasmalogen

 

any of a group of naturally occurring lipids belonging to phosphoglycerides, or phosphatides. Plasmalogens were first discovered in 1924 in blood plasma. They are widely distributed in animal tissues, for example, the brain, heart, and skeletal muscles, as well as in plant tissues, for example, algae and the fruits of leguminous plants.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Since [alpha]-chloro fatty aldehydes can exclusively be generated by plasmalogen oxidation, this emphasizes the important role of these alkenyl ether lipids and the interest plasmalogens is currently attracting.
Biochemical investigations like RBC plasmalogen levels and phytanic acid levels could not be done because of financial constraints.
Further biochemical studies showed high phytanic acid (9.2; n < 5.28 [micro]mol/L) and low plasmalogen (3.2; n > 6.6) levels.
Engelmann, "Delayed oxidative degradation of polyunsaturated diacyl phospholipids in the presence of plasmalogen phospholipids in vitro," Biochemical Journal, vol.
Ether glycerolipid (plasmalogen) biosynthesis: DHAP-ATPase, alkyl-DHAP synthase 4.
Relative high percentages of the plasmalogen derivatives 16:0DMA and 18:0DMA were also detected.
Analyses of the fatty acid pattern of membrane phospholipids and plasmalogen of human spermatozoa have demonstrated significant levels of polyunsaturated acids.
Overall, cells treated with 10 [micro]M MEHP showed significantly higher levels of all glycerolipids (FA, MG, DG), PC, PS, phosphatidylserine plasmalogens (PS-P), and phosphatidic acid plasmalogens (PA-P) than cells treated with 0.1 [micro]M MEHP or controls showed.
These products are highly reactive and will oxidize plasmalogens, which are enriched in lung and surfactant, to form chlorinated lipids (Cl-lipids), 2-chloropalmitaldehyde and 2-chlorostearalddehyde.
Ishikawa et al., "Myo-inositol treatment increases serum plasmalogens and decreases small dense LDL, particularly in hyperlipidemic subjects with metabolic syndrome," Journal of Nutritional Science and Vitaminology (Tokyo), vol.
Juaneda et al., "Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma," Experimental Eye Research, vol.