Because
Platinol was available, however, FDA would approve Paraplatin
In the cytotoxicity assays, for HepG2, K562 and MCF-7 cell lines, adriamycin at concentration of 4 [micro]g/ml was choose as reference drug, while HL60 is
platinol, with the final concentration is 4 [micro]g/ml, too.
Studies estimate that generic competition after successful patent challenges involving just four major brand-name drugs (Prozac,
Platinol, Taxol, and Zantac) has saved TPPs and consumers more than $9 billion.
For non-small cell lung cancer, national guidelines call for the use of carboplatin (Paraplatin) and/or cisplatin (
Platinol), in combination with a second drug.
* Carboptatin (Paraplatin) is included in combination with paclitaxel (Taxol) as an alternative to current combination regimens based on cisplatin (
Platinol) for adjuvant chemotherapy.
* Carboplatin (Paraplatin) is included in combination with paclitaxel (Taxol) as an alternative to current combination regimens based on cisplatin (
Platinol) for adjuvant chemotherapy.
In another action, the Commission charged that Bristol-Myers Squibb Company (Bristol) engaged in a series of anticompetitive acts over the past decade to obstruct the entry of low-price generic competition for three of its widely-used pharmaceutical products: two anticancer drugs, Taxol and
Platinol, and the antianxiety agent BuSpar.
Methotrexate and Cytoxan (cyclophosphamide) are associated with more moderate hair loss, and it's rare to have alopecia with
Platinol AQ (cisplatin) use.
Bristol-Myers Squibb--whose oncology operation rests on such in-licensed drugs as Paraplatin,
Platinol, and Taxol--derives more than 95 percent of its oncology revenues from in-licensed products.