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(plo͝or`ĭsē), inflammation of the pleura (the membrane that covers the lungs and lines the chest cavity). It is sometimes accompanied by pain and coughing. The inflammation may be dry or it may be accompanied by an effusion, or fluid, that fills the chest cavity; when the effusion is infected, the condition is known as empyema. The dry type of pleurisy usually occurs in association with bacterial infections such as pneumonia. Pleurisy with effusion is often associated with such chronic lung conditions as tuberculosis or tumors. Immune disorders such as lupus and rheumatic fever tend to have recurrent pleurisy, with or without effusion. Epidemic pleurodynia, a pleurisy attributed to a virus, is a mild disease of short duration. Treatment of pleurisy is directed at the underlying condition as well as the symptoms.



inflammation of the pleura.

Pleurisy may be infectious or noninfectious. The causative agents in man and animals include the Mycobacterium tuberculosis, cocci, and viruses. In man the most common types are tubercular pleurisy, with primary localization of the infection in the lung or in the lymph nodes, and pleurisy as a complication of inflammation of the lungs. Forms of noninfectious pleurisy are toxic pleurisy, which arises when the pleura is irritated by toxic metabolic products, such as the nitrogenous residues that occur with uremia; traumatic pleurisy; and pleurisy occurring with tumors of the lungs or of the pleura itself. Another form of the disease is primary, or idiopathic, pleurisy, whose etiology has not been established.

Fibrinous pleurisy, with deposit of a dry exudate, fibrin, on the pleurae, occurs with tuberculosis and pneumonia. Exudative pleurisy, in which the fissure between the pleurae is filled with an exudate, may be serous or serofibrinous (tubercular, idiopathic, or rheumatic), hemorrhagic (tubercular or with tumors), or purulent and putrefactive (as with lung abscesses). Pleurisy may be acute or chronic and localized or diffuse.

The symptoms of pleurisy are malaise, fever, chills, perspiration, cough, dyspnea, and changes in the blood’s composition. With dry pleurisy there is pain in the thorax and the sound of pleural friction with auscultation. With exudative pleurisy, a dulling of pulmonary sound is revealed by percussion; diverticulum of the thorax in the region of the exudate may occur, and respiration is severely attenuated. The data of X-ray diagnosis are important. Adhesions may remain after pleurisy. The disease is treated by antibiotics and by antiallergic, anti-inflammatory, and symptomatic agents. The exudate is removed by means of pleurocentesis.


Abrikosov, A. I. Chastnaiapatologicheskaia anatomiia, fasc. 3. Moscow, 1947.
Rabukhin, A. E. Tuberkuleznye plevrity. Moscow, 1948.
Bolezni sistemy dykhaniia. Edited by T. Garbin’skii. Warsaw, 1967.



Inflammation of the pleura. Also known as pleuritis.


inflammation of the pleura, characterized by pain that is aggravated by deep breathing or coughing
References in periodicals archive ?
2) The patient may also present with pleuritic chest pain, pericarditis, and rarely even a tension fecopneumothorax should intrathoracic perforation occur.
Her pleuritic chest pain was partially relieved with nonsteroidal anti-inflammatory drugs.
In January 2011 (wet season), a 15-year-old previously healthy Polynesian boy was examined for a 3-day history of fever, myalgia, fatigue, headache, sore throat, pleuritic chest pain, and vomiting.
A 49 year old woman presented with left sided pleuritic chest pain, nonproductive cough and progressive exertional dyspnea for two months.
Clinical findings can therefore vary considerably from neck pain and swelling associated with thrombophlebitis to pleuritic chest pain, haemoptysis, dyspnoea or arthralgia as a result of septic thromboemboli.
He also complained of pleuritic chest pain and aching pains in his lower back and neck.
He presented to the emergency department with acute onset shortness of breath, dizziness, and pleuritic chest pain that started 1 week previously and resolved slowly over 3 to 4 days.
54-year-old woman with end stage renal disease on chronic hemodialysis presented with pleuritic chest pain.
Subjects: A total of 3,306 patients with clinically suspected PE, defined as a sudden onset of dyspnea or pleuritic chest pain, or sudden worsening of existing dyspnea, without another apparent cause, were enrolled.
3], similar to the ambient air concentrations reported in Libby, had significantly elevated radiographic pleural changes and pleuritic chest pain.
A 30-year-old African American man presented to the hospital with a 2-week history of a productive cough, shortness of breath, chills, hemoptysis, and pleuritic chest pain in the left posterior chest.