polyadenylation

(redirected from Polyadenosine)
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polyadenylation

[‚päl·ē·ə‚den·ə′lā·shən]
(cell and molecular biology)
The addition of adenine nucleotides to the 3′ end of messenger ribonucleic acid molecules during posttranscriptional modification.
References in periodicals archive ?
Second, a trial on polyadenosine diphosphate-ribose polymerase (PARP) inhibitors as maintenance therapy after adjuvant chemotherapy showed that women with a BRCA mutation had a progression-free survival benefit of nearly 3 years.
Polyadenosine diphosphate (ADP) ribose polymerase (cleaved PARP; caspases 3, 7, and 9; cleaved caspases 3, 7, and 9; and B-cell lymphoma-2 (Bcl-2)) and Bcl-2-associated X protein (Bax) antibodies were from Cell Signaling Technology (Danvers, MA, USA).
This domain can bind polyadenosine diphosphate-ribose regions and could play a role in the replication or transcription of virus RNA.