As commonly seen in aggressive lung cancers, HOA is characterized by digital clubbing, periosteal bone proliferation, and an arthropathy ranging from arthralgia to polyarthritis
. The pathogenesis is unclear; however, vascular endothelial growth factor may play a role in the development of HOA (10).
We thank Anne Laurence Thomi Georgelin, who referred the patient to the Necker-Pasteur Center for Infectious Diseases and Tropical Medicine; Valerie Zeller for the management of septic polyarthritis
; and Philippe Lanotte and Marie-Pierre Dubrana, who participated in molecular analysis.
ACR criteria included age less than 16 years, signs of arthritis in one or more joints, disease duration 6 weeks or longer, onset type defined in first 6 months (i) Polyarthritis
: when 5 or more inflamed joints; (ii) Oligoarthritis: when less than 5 joints and (iii) systemic onset disease: Arthritis with characteristic fever and exclusion of other forms of juvenile arthritis.
The disease onset is usually acute and it is commonly associated with asymmetrical monoarthritis or polyarthritis
of large joints, predominately of lower extremities.
It is mostly idiopathic; nevertheless, underplaying immunological anomalies have been recognized.2 Fifty percent of the patients have underlying systemic diseases such as inflammatory bowel diseases, polyarthritis
, diverticulosis, paraproteinaemia, myeloma, leukaemia, active chronic hepatitis, and Behcet syndrome.1 There are four known variants of pyoderma gangrenosum; ulcerative, pustular, bullous and superficial.3
She suffers from a rare disease that affects her lymph system and internal organs - Stage 4 sarcoidosis and neurosarcoidosis -- and has battled several other complications including osteoporosis, skin cancer, polyarthritis
, stroke, epilepsy, meningiomas and pneumonia.
The dog showed blindness which may be due to ehrlichiosis with multisystemic signs such as polyarthritis
, neurologic signs due to meningitis and ocular signs such as anterior uveitis, chorioretinitis, pappiledema, retinal perivascular infiltrate and retinal haemorrhage.
RA is a symmetric, inflammatory, peripheral polyarthritis
of unknown etiology.
46 year old Indian male, non-smoker, married, nondiabetic, normotensive admitted at department of internal medicine in our hospital with history of high grade fever, polyarthritis
, and skin rash for the last 4 weeks.
The musculoskeletal manifestation can range from oligo/polyarthritis, spondylodiscitis, and even erosive destructive polyarthritis
Indeed, articular pain, atrophy of the fingers, and polymorphic cutaneous manifestations often evoke rheumatoid arthritis or deforming polyarthritis
. However, the diagnosis of musculoskeletal injury due to leprosy is difficult, given its multiple manifestations and the fact that many autoimmune disorders are part of differential diagnosis .
Clopidogrel has been associated with a rare but severe adverse drug event (ADE) of polyarthritis
in several case reports.