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Given the limited availability of hydroxyamphetamine and the similarities in sensitivity and specificity of the two drugs in localising a lesion to the postganglionic neuron, phenylephrine 1% appears to be the more reliable and readily available alternative.
1988), demonstrated that brevetoxin-induced contractile effects can be blocked with atropine but not with a histamine antagonist, suggesting that toxin-induced constriction results from stimulation of parasympathetic postganglionic neurons. In contrast to the prior in vitro findings, however, our in vivo studies showed that protective effects were achieved with the mast cell stabilizer cromolyn sodium and the histamine [H.sub.1]-antagonist diphenhydramine.