The conditions considered as pre-malignant
are leukoplakia, lichen planus, oral submucous fibrosis and erythroplakia.
Cholesterolosis, xanthogranulomatous cholecystitis, benign polyps, pre-malignant
and malignant conditions are the less common pathological entities6.
Among their topics are flexible laser carbon-dioxide laser and trans-oral robotic surgery, benign and pre-malignant
lesions of the larynx, trans-oral laser microsurgery of the oral cavity, laser salvage surgery after failed radiotherapy, and quality of life after trans-oral laser microsurgery.
8 Hence, a good number of patients in pre-malignant
stage are being missed.
Objective: To evaluate salivary detection of HPV-16 and 18 would be feasible and informative biomarker for oral pre-malignant
and malignant lesion in our population.
The 63-year-old was later told by an independent medical expert that his prostate gland was pre-malignant
, that he did not have cancer and that he did not need the operation.
Almost all patients with multiple myeloma progress from an initial, asymptomatic pre-malignant
stage to established disease.
The study compared the effects of EGCG in human oral squamous carcinoma cells, pre-malignant
cells, and normal human gingival fibroblasts.
What we are primarily detecting here is an early, pre-malignant
stage in which the cells have acquired just one initiating mutation.
The research's ultimate goal is to develop a targeted strategy to prevent pre-malignant
lesions from forming by targeting the biology of these lesions and therefore preventing lung cancer from developing.
Screening and an early detection are believed to decrease both the morbidity and mortality which are associated with oral SCC, because unlike many anatomic sites, in the oral cavity, pre-malignant
lesions are often visible on clinical examination.
Study co-author Debanjan Dhar said that it was never established whether dysplastic lesions are just a regenerative (healing) response of the liver triggered by tissue damage or are actually pre-malignant
lesions that harbour tumour progenitor cells.