caspase

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caspase

[′kas‚pās]
(cell and molecular biology)
Any of a family of intracellular proteins that mediate apoptosis.
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At the same time, these proteins recruit key molecules that are responsible for mediating the intracellular signal, among these, procaspase 8 and subsequent formation of the DISC complex [13-15, 35].
Pancreatic Beta Cell Death: Novel Potential Mechanisms in Diabetes Therapy
Primary antibodies for procaspase 3, caspase 8, caspase 9, CDK6, p53, and cleaved PARP were purchased from Cell Signaling Technology (Beverly, MA).
Antineoplastic Effects of Honokiol on Melanoma
Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation.
Identification of gene markers for formaldehyde exposure in humans
Cleavage of inactive procaspases to active caspase enzymes is a hallmark of apoptosis.
Melissa officinalis extract induces apoptosis and inhibits proliferation in colon cancer cells through formation of reactive oxygen species
IFN can also induce the synthesis of gene products that arrest the cell cycle such as p21 and thus block virus replication, or induce a pro-apoptotic state such as procaspases. IFN can induce the synthesis of proteins that are involved in the processing and presentation of virus proteins to [CD8.sup.+] cytotoxic T lymphocytes.
Xanthohumol enhances antiviral effect of interferon [alpha]-2b against bovine viral diarrhea virus, a surrogate of hepatitis C virus
The mitochondria is the central regulator of the intrinsic pathway of apoptosis and that is accompanied by the release of procaspases, cytochrome c, apoptotic protease-activating factor 1 (Apaf-1), endonuclease G and apoptosis-inducing factor (Green 2000).
Green tea polyphenols for prostate cancer chemoprevention: A translational perspective

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