Frequency is pioneering a new class of small-molecule therapeutics designed to activate progenitor cells
already present within the body to create healthy functional tissues and organs.
Berweiler et al., "Estrogen increases bone marrow-derived endothelial progenitor cell
production and diminishes neointima formation," Circulation, vol.
The body's endothelial progenitor cells
repair the damage to the lining of the arteries that leads to cardiovascular disease.
Hybrid vitronectin-mimicking polycaprolactone scaffolds for human retinal progenitor cell
differentiation and transplantation.
According to the new Services Agreement, Progenitor Cell
Therapy will produce clinical supplies of ICT-140, a dendritic cell vaccine targeting seven ovarian cancer antigens, using process improvements.
A strong, positive correlation was identified between coronary collateral flow and the number of circulating CD34+/CD133+ endothelial progenitor cells
in patients with CAD.
The deal has already received support from the owners of above 50% in both NeoStem and Progenitor Cell
The human progenitor cell
antigen (CD34) is localized on endothelial cells, dermal dendritic cells and peri-follicular cells in formalin--fixed normal skin, and on poliferating endothelial cells and stromal spindle--shaped cells in Kaposi's Sarcoma.
(7,8) Jones and Corwin have proposed that a subpopulation of cells localized in the supporting cell layer in mammals may be progenitor cells
that are responsible for limited hair cell regeneration in vestibular organs such as the utricle.
CBMG's allogeneic adipose-derived mesenchymal progenitor cell
(haMPC) AlloJoin product is an off-the-shelf stem cell therapy developed completely in -house by CBMG over the past 7 years.
Founded by pioneers in the field of regenerative medicine and drug delivery technology, Frequency's Progenitor Cell
Activation Regeneration platform uses a combination of small molecules to stimulate progenitor cells
within the body to repair diseased or damaged tissue.
In order to understand how progenitors decide where to go in the noisy environment of animal regeneration, the researchers used the planarian eye, a visible organ that is small enough to be removed without serious injury and has the added advantage of having defined progenitor cell