progenitor cell

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progenitor cell

[prə′jen·əd·ər ‚sel]
(cell and molecular biology)
A precursor cell that completes a series of cell divisions to produce a distinct cell lineage.
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The cells in the study were differentiated further down the beta cell lineage than the PEC-01(TM) pancreatic progenitor cells being tested in ViaCyte's VC-01 product candidate, which is currently in a Phase 1/2 clinical trial for treatment of type 1 diabetes.
A team led by neurosurgeon Viviane Tabar, MD, and research associate Jinghua Piao, PhD, of the Memorial Sloan Kettering Cancer Center in New York City, wondered whether stem cells could be coaxed to replace these lost oligodendrocyte progenitor cells.
In particular, when naming products, companies are advised to use the term neural rather than neuronal, both in reference to stem cells and progenitor cells, in order to best position products within the marketplace.
Previously, the researchers had transplanted human glial progenitor cells into the brains of mice that had a genetic disorder mimicking multiple sclerosis.
Progenitor cells are more limited, typically differentiating into a specific type of cell and able to divide only a fixed number of times.
Participants in the three year study will undergo a single bone marrow collection procedure, from which neural progenitor cells will be isolated, expanded and tested prior to injection.
Stem cells in the scalp normally develop into progenitor cells, which in turn give rise to new hair growth.
These so-called progenitor cells, described in a report in the journal Science, should also lead to better ways to study heart disease and to test drugs, the researchers said.
In an attempt to identify the possible source of cells which maintain the tissue turnover, we used CD 34, a well established marker of peripheral blood stem cell in healthy human gingiva to determine the origin of progenitor cells in healthy gingiva.
Endothelial progenitor cells (EPCs), which circulate in the bloodstream, play a role in normal blood vessel function and may find application as both a marker of cardiovascular disease and a potential treatment, according to a recent review.
The cell enrichment methods employ reagents that specifically recognize CD9 and CD41, in conjunction with other markers expressed on lineage committed progenitor cells.