prohormone

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prohormone

[′prō‚hȯr‚mōn]
(biochemistry)
The precursor of a hormone.
References in periodicals archive ?
In contrast to other prohormones, proBNP does not contain a C-terminal-flanking region.
We speculate that any differences will become more pronounced as cardiac failure worsens, possibly leading to less efficient processing of the prohormones. Using proANP measurement as a molecular marker within heart failure must take into account the possibility that the endogenous peptides might differ as a function of cardiac status.
[7] Nonstandard abbreviations: HF, heart failure; ANP, A-type (atrial) natriuretic peptide; BNP, B-type natriuretic peptide; NT-proANP and NT-proBNP, amino-terminal fragment of the ANP and BNP prohormone, respectively; MR-proANP, midregion of the ANP prohormone; AUC, area under the curve; CI, confidence interval; and eGFR, estimated glomerular filtration rate.
As mentioned, both ANP and BNP are synthesized as prohormones and require posttranslational processing to release the highly potent natriuretic peptides.
The analysis of "non-hormonal" nutritional supplements for prohormones. In: Schanzer W, Geyer H, Gotzmann A, Mareck-Engelke U, eds.
The endocrinologically active C-terminal peptides (ANP and BNP) and their N-terminal prohormone fragments are found in plasma.
A selection of products included in the study were advertised as 'prohormones', with researchers suggesting they could be misconstrued as legal replacements for steroids (http://www.ukad.org.uk/news/article/research-highlights-risk-of-steroids-in-supplements).
Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function.
(17, 26) With respect to the latter, in male and female supplement users who, because of this condition, are considered to be at a higher risk, the frequency was 15.9%, (15) and with regard to the use of specific substances, in adolescents and university students the following are reported: ephedrine, 3.8-6% (29); testosterone derivatives, 2-5.8%, (26) and prohormones, 3.8-4.5%.
Others include: anabolic steroids prohormones creatine amino acids protein caffeine and antioxidants.
It has been shown in a previous study that ~15% of dietary supplements comprising mainly vitamins, minerals, proteins and creatine contained undisclosed anabolic androgenic steroids.[2] These steroids were mainly prohormones, referring to androgenic precursors that are enzymatically activated in vivo to the anabolic steroid testosterone and its derivatives.