Also found in: Dictionary, Medical, Wikipedia.
Related to Pronephros: mesonephros, metanephros


One of the anterior pair of renal organs in higher vertebrate embryos; the pair initiates formation of the archinephric duct.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



the excretory organ in the embryos of lower vertebrates; in higher vertebrates, including man, the pronephros is vestigial and nonfunctional. During embryonic development, the pronephros is replaced by the mesonephros. In most taxonomic groups the excretory ducts of the pronephros have a single filtering apparatus—a vascular glomerulus located near the funnel (nephrostome) through which each tubule of the pronephros opens into the coelom. The other ends of the tubules merge and form the rudiment of the pronephrotic canal, which grows toward the posterior end and terminates in the cloaca.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
The miR-30 miRNA family regulates Xenopus pronephros development and targets the transcription factor Xlim1/Lhx1.
In addition to cytokines, the immune system of teleost fishes is regulated by neuroendocrine interactions, primarily through the hypothalamic-pituitary-interrenal (HPI) axis, because the pronephros, in addition to their roles as lymphoid organs, has important endocrine functions.
Antibody-farming cells in the pronephros the teleost: Lepomis macrochirus.
We have begun a study to image [Ca.sup.2+] signaling during the formation of the pronephros (the functional embryonic kidney) in both intact zebrafish and Xenopus laevis embryos, as well as in Xenopus animal caps that are isolated at the blastula stage and induced to differentiate into pronephric tubules by incubation with retinoic acid (RA) and activin A (AA).
Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis.
The 125-[micro]M dose resulted in expression in epithelial cells of the developing skin, gill, olfactory organ, digestive tract, liver, pronephric ducts of the pronephros, and in the lateral line neuromasts (Figure 3).